Protein Info for PP_1779 in Pseudomonas putida KT2440

Annotation: Lipopolysaccharide ABC export system, ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 405 PF00005: ABC_tran" amino acids 40 to 172 (133 residues), 83.7 bits, see alignment E=2e-27 PF14524: Wzt_C" amino acids 258 to 397 (140 residues), 147.3 bits, see alignment E=3e-47

Best Hits

KEGG orthology group: K09691, lipopolysaccharide transport system ATP-binding protein (inferred from 100% identity to ppu:PP_1779)

MetaCyc: 58% identical to O:8-antigen ABC transporter ATP-binding subunit (Escherichia coli O8)
TRANS-RXN-445 [EC: 7.5.2.14]

Predicted SEED Role

"ATP binding component of ABC-transporter"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88LZ7 at UniProt or InterPro

Protein Sequence (405 amino acids)

>PP_1779 Lipopolysaccharide ABC export system, ATP-binding protein (Pseudomonas putida KT2440)
MSLLSVSDVGKAYKTYRSELQRIAHWFFLPTKASSEHWVLKHINFAIEPGEAIGIIGQNG
AGKSTLLKMITGTLQPTQGRVQVNGRIAAILELGMGFNPELSGRQNVYHAAGLMGFDVQQ
INDVIDDIEAFAEIGEYFDEAVRTYSSGMQMRVAFAVATAFRPEILIVDEALSVGDSYFQ
HKSFERIREFQRLGTSLLIVSHDRGAIQSLCSRALLLENGSIIKDGPPEQVMDYYNALIA
EKENSTVQVKQLADGTVQTQSGSGEATIGTVALYDMQGTPVEFVAVGDKVTLSVQVEVHA
PIPELVVGYVIKDRLGQHVFGTNTHHLGKAQKALETGEKLEYRFDFEMNLGPGSYSVAVA
LHANEVHIGSNYEWRDLALVFNVVNTSKPQFVGMAWVPTAVECIR