Protein Info for PP_1763 in Pseudomonas putida KT2440

Annotation: putative oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF00106: adh_short" amino acids 14 to 210 (197 residues), 159 bits, see alignment E=1.6e-50 PF08659: KR" amino acids 16 to 181 (166 residues), 30.5 bits, see alignment E=5e-11 PF13561: adh_short_C2" amino acids 20 to 243 (224 residues), 121.5 bits, see alignment E=6.6e-39

Best Hits

Swiss-Prot: 51% identical to YCIK_ECOLI: Uncharacterized oxidoreductase YciK (yciK) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_3951)

MetaCyc: 53% identical to CAI-1 synthase (Vibrio cholerae O1 biovar El Tor str. N16961)
1.1.1.-

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88M12 at UniProt or InterPro

Protein Sequence (246 amino acids)

>PP_1763 putative oxidoreductase (Pseudomonas putida KT2440)
MFDYTARPDLLQGRVILVTGAGRGIGAAAAKAYAALGATVLLLGKTEANLNEVYDQIEAA
GHPQPVVIPFNLETALPHQYDELAAMIEGQFGRLDGLLNNASIIGPRTPLEQLSGDNFMR
VMHINVNATFMLTSTLLPLLKLSEDASVVFTSSSVGRKGRAYWGAYGVSKFATEGLMQTL
ADELEGVAPVRANSINPGATRTAMRAQAYPGENPQNNPLPEEIMPVYLYLMGPDSTGVNG
QAFNAQ