Protein Info for PP_1291 in Pseudomonas putida KT2440

Annotation: PhoH family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 464 PF13638: PIN_4" amino acids 16 to 160 (145 residues), 115.8 bits, see alignment E=2.7e-37 PF02562: PhoH" amino acids 255 to 447 (193 residues), 142.4 bits, see alignment E=2.1e-45 PF05707: Zot" amino acids 279 to 397 (119 residues), 20.6 bits, see alignment E=4.4e-08

Best Hits

KEGG orthology group: K07175, PhoH-like ATPase (inferred from 100% identity to ppu:PP_1291)

Predicted SEED Role

"Predicted ATPase related to phosphate starvation-inducible protein PhoH" in subsystem Phosphate metabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88NC1 at UniProt or InterPro

Protein Sequence (464 amino acids)

>PP_1291 PhoH family protein (Pseudomonas putida KT2440)
MDDQGRNPSSSKPILYVLDTNVLIHDPNALLNFEEHHVAIPMTVLEELDKLKTGKQSIAA
ECRQAIRLIDQTLGDASPSDVEQGVPIQRNKSGPKGFLSILMTPRNEPNKLLPENLNDNI
IINQLLEVRARRTDLDVVLVTKDINMRLKARACGIAAEDYSTDQLVDDVSLLSKGYHSVT
GSFWDRVSKVDTRQERGRTWHRVQMIDNLPAVHVNEFIIDEQGFVGWIKGIRDDELLLLD
LHQEPLLHQEAWGLKPRDIHQSLALFALLDPDIHLVNLTGAAGSGKTILALAAAIEQTMV
SKRYRRIIATRSVQGLDQEIGFLPGTEAEKMEPWLGAITDNLEALHMDDESTHGSVEYIL
ERVPLQFKSLNYIRGRSFQQSLILIDECQNLTPHQMKTIITRAGSGSKVVCLGNLAQIDT
PYLSATSSGLTYLTERFKDFPHGVHITLQGVPRSVLAEYAESHL