Protein Info for PP_1259 in Pseudomonas putida KT2440

Annotation: Aspartate-proton symporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 537 transmembrane" amino acids 12 to 31 (20 residues), see Phobius details amino acids 43 to 63 (21 residues), see Phobius details amino acids 84 to 107 (24 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 159 to 179 (21 residues), see Phobius details amino acids 199 to 220 (22 residues), see Phobius details amino acids 232 to 253 (22 residues), see Phobius details amino acids 279 to 298 (20 residues), see Phobius details amino acids 339 to 356 (18 residues), see Phobius details amino acids 362 to 384 (23 residues), see Phobius details amino acids 397 to 417 (21 residues), see Phobius details amino acids 423 to 440 (18 residues), see Phobius details amino acids 460 to 483 (24 residues), see Phobius details amino acids 489 to 508 (20 residues), see Phobius details PF13520: AA_permease_2" amino acids 9 to 450 (442 residues), 164.6 bits, see alignment E=3.8e-52 PF00324: AA_permease" amino acids 14 to 385 (372 residues), 85.4 bits, see alignment E=3.7e-28

Best Hits

Swiss-Prot: 59% identical to ASPP_BACSU: Aspartate-proton symporter (yveA) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to ppu:PP_1259)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88NF2 at UniProt or InterPro

Protein Sequence (537 amino acids)

>PP_1259 Aspartate-proton symporter (Pseudomonas putida KT2440)
MSGKFKKQLSLLDLTFIGLGAIFGSGWLFAASHVSAIAGPAGILSWFLGGFAVLLLGIVY
CELGAALPRAGGVVRYPVYSHGPLLGYLMGFITLIAFSSLIAIEVVASRQYAAAWFPGLT
KAGSSDPTVLGWLVQFALLGLFFFLNYRSVKTFAKANNLVSVFKFIVPLLVIGVLFTFFK
PENFEVQGFAPFGLSGVEMAVSAGGIIFAYLGLTPIISVASEVKNPQRTIPIALILSVLL
STAIYALLQLAFLGSVPTEMLANGWASVTKELALPYRDIALALGVGWLAYLVVADAVISP
SGCGNIYMNATPRVIYGWAQTGTFFKYFTRIDAESGIPRPALWLTFGLSVFWTLPFPSWE
ALINVVSAALVLSYAVAPVSVAALRRNAPHMPRPFRVKGMTVLGPLSFIIAALIVYWSGW
NTVSWLLALQIVMFVLYLLCSRFVPTQHLSLGQQVRSSAWLIGFYALTILLSWLGSFGGL
GVIGHPFDTVVVAACALGIYYWGAATGVPAHLVRLEGDDESEACAETSNGRPVAVAS