Protein Info for PP_1253 in Pseudomonas putida KT2440

Annotation: Transcriptional regulator, ArsR family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 111 PF12840: HTH_20" amino acids 33 to 79 (47 residues), 44.5 bits, see alignment E=1.2e-15 PF01022: HTH_5" amino acids 35 to 79 (45 residues), 24.8 bits, see alignment E=1.6e-09

Best Hits

Swiss-Prot: 46% identical to YCZG_BACSU: Uncharacterized HTH-type transcriptional regulator YczG (yczG) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_1280)

Predicted SEED Role

"Transcriptional regulator, ArsR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88NF8 at UniProt or InterPro

Protein Sequence (111 amino acids)

>PP_1253 Transcriptional regulator, ArsR family (Pseudomonas putida KT2440)
MAINETPVIMSTMRAYKHPNPDDLILERLLYALSDPVRLEIVRHLAGVAEASCGELDGGR
PKSSMSHHFRVLRDAGLVQTRNVGTTHMNSLRSEMLGERFPGLLECILRQQ