Protein Info for PP_1039 in Pseudomonas putida KT2440

Annotation: sec-independent protein translocase protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 253 transmembrane" amino acids 27 to 49 (23 residues), see Phobius details amino acids 76 to 99 (24 residues), see Phobius details amino acids 112 to 141 (30 residues), see Phobius details amino acids 161 to 187 (27 residues), see Phobius details amino acids 199 to 216 (18 residues), see Phobius details amino acids 222 to 240 (19 residues), see Phobius details TIGR00945: twin arginine-targeting protein translocase TatC" amino acids 13 to 230 (218 residues), 232.4 bits, see alignment E=2.8e-73 PF00902: TatC" amino acids 15 to 225 (211 residues), 229 bits, see alignment E=2.8e-72

Best Hits

Swiss-Prot: 68% identical to TATC_AZOCH: Sec-independent protein translocase protein TatC (tatC) from Azotobacter chroococcum mcd 1

KEGG orthology group: K03118, sec-independent protein translocase protein TatC (inferred from 99% identity to ppf:Pput_1080)

MetaCyc: 56% identical to twin arginine protein translocation system - TatC protein (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-181

Predicted SEED Role

"Twin-arginine translocation protein TatC" in subsystem Cluster-based Subsystem Grouping Hypotheticals - perhaps Proteosome Related or Twin-arginine translocation system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88P14 at UniProt or InterPro

Protein Sequence (253 amino acids)

>PP_1039 sec-independent protein translocase protein (Pseudomonas putida KT2440)
MSIAMDPAASMPLTEHLRDLRKRLVRCLALVALVFAGLFPFAQTLYTLISEPLRRFLPEG
ASMIATSVTSPFLAPFKLTAMCALFLAMPLLLHQAWGFLAPGLYRRERRIALPLLVSSIV
LFYAGMAFAFFLVFPMMFGFFASVTPDGVAMMTDISQYLDFILALFLAFGLAFEIPVATF
IVVWAGLADVATLRRSRPYVVVGCFVVGMILTPPDVFSQTMLAVPMWVLFEMGLLACGML
KRPEPGKEIVAGL