Protein Info for PP_0946 in Pseudomonas putida KT2440

Annotation: superoxide dismutase (Mn)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00081: Sod_Fe_N
  • amino acids 10 to 96 (87 residues), 117.6 bits, E=2.8e-38
• PF02777: Sod_Fe_C
  • amino acids 104 to 204 (101 residues), 130.7 bits, E=2e-42

Best Hits

Swiss-Prot: 94% identical to SODM_PSEPU: Superoxide dismutase [Mn] (sodA) from Pseudomonas putida

KEGG orthology group: K04564, superoxide dismutase, Fe-Mn family [EC: 1.15.1.1] (inferred from 100% identity to ppf:Pput_0985)

Predicted SEED Role

"Manganese superoxide dismutase (EC 1.15.1.1)" in subsystem Nitric oxide synthase or Oxidative stress (EC 1.15.1.1)

MetaCyc Pathways

• reactive oxygen species degradation (4/4 steps found)
• ethene biosynthesis III (microbes) (6/7 steps found)
• superoxide radicals degradation (2/2 steps found)

Isozymes

Compare fitness of predicted isozymes for: 1.15.1.1

Use Curated BLAST to search for 1.15.1.1

Sequence Analysis Tools

See Q88PA4 at UniProt or InterPro

Protein Sequence (210 amino acids)

>PP_0946 superoxide dismutase (Mn) (Pseudomonas putida KT2440)
MPTEFTDMPHTLPALPYAYDALEPHIDAQTMEIHHTKHHQTYVNGLNAALEGTEWAEWPV
EKLVAAVKQLPENLRGAVTNHGGGHANHSLFWTVMSPQGGGEPVGQLAQAVTAQLGGFEA
FKEAFTKAALTRFGSGWAWLSVTPQKTLMVESSGNQDSPLMHGNAPILGLDVWEHAYYLK
YQNRRPEYIGAFYNVIDWVEVERRYLEALK