Protein Info for PP_0429 in Pseudomonas putida KT2440

Annotation: Oxidoreductase, short chain dehydrogenase/reductase family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 260 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF00106: adh_short" amino acids 4 to 189 (186 residues), 148.4 bits, see alignment E=3.8e-47 PF01370: Epimerase" amino acids 6 to 125 (120 residues), 20.9 bits, see alignment E=4.3e-08 PF08659: KR" amino acids 6 to 169 (164 residues), 48 bits, see alignment E=2.8e-16 PF13561: adh_short_C2" amino acids 9 to 188 (180 residues), 100 bits, see alignment E=3.3e-32

Best Hits

KEGG orthology group: K07124, (no description) (inferred from 99% identity to ppg:PputGB1_0459)

Predicted SEED Role

"Oxidoreductase, short chain dehydrogenase/reductase family" in subsystem Ribitol, Xylitol, Arabitol, Mannitol and Sorbitol utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88QQ9 at UniProt or InterPro

Protein Sequence (260 amino acids)

>PP_0429 Oxidoreductase, short chain dehydrogenase/reductase family (Pseudomonas putida KT2440)
MTRYAMITGASSGLGLALAEALARRGRNLILVARQRETLEPVAIELTQRFGVEVLFRACD
LSQPLRLSGFVLELEEGERRIDLLVNCAGLRTYGPFLAHEWADEQDLLEVNVLALSRLCH
AIGNLMAVQGGGQILNVAGLAGVAPGPWMAAYAASKAYVLSFSQALREELKRTGIKVSVL
CPGPVRSARRRIARLDGKPRCLSPEEVALYTVRALDKNRALIMPGRRNRWLAFAPRLLPR
WLVRKLAGAIHRRYCPSGME