Protein Info for PP_0405 in Pseudomonas putida KT2440

Annotation: conserved protein of unknown function

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01636: APH
  • amino acids 36 to 267 (232 residues), 133.6 bits, E=5.2e-43

Best Hits

Swiss-Prot: 100% identical to AMGK_PSEPK: N-acetylmuramate/N-acetylglucosamine kinase (amgK) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)

KEGG orthology group: K07102, (no description) (inferred from 99% identity to ppf:Pput_0439)

MetaCyc: 100% identical to N-acetyl-D-muramate 1-kinase (Pseudomonas putida KT2440)
RXN-18660 [EC: 2.7.1.221]; N-acetylhexosamine 1-kinase. [EC: 2.7.1.221, 2.7.1.162]; N-acetylgalactosamine kinase. [EC: 2.7.1.221, 2.7.1.162, 2.7.1.157]

Predicted SEED Role

No annotation

MetaCyc Pathways

• peptidoglycan recycling II (8/10 steps found)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.157 or 2.7.1.162 or 2.7.1.221

Sequence Analysis Tools

See Q88QT3 at UniProt or InterPro

Protein Sequence (339 amino acids)

>PP_0405 conserved protein of unknown function (Pseudomonas putida KT2440)
MPEHDVRLQQLTVWLDEQLNDLFRDNAWGEVPAGSLTAASSDASFRRYFRWQGAGHSFVI
MDAPPPQENCRPFVAIDHLLASADVHVPLIHAQDLERGFLLLGDLGTQTYLDIINADNAD
GLFADAIDALLKFQRLPMDAPLPSYDDALLRREVELFPEWYVGRELGLTFTDAQKATWQR
VSQLLIDSALAQPKVLVHRDYMPRNLMQSTPNPGVLDFQDAVYGPVTYDITCLFKDAFVS
WPQARVEGWLGDYWQQAQAAGIPVHAEFEAFHRASDLMGVQRHLKVIGIFARICHRDGKP
RYLGDVPRFFAYINEVIGRRPELAELGELIAELQAGARA