Protein Info for PP_0359 in Pseudomonas putida KT2440

Annotation: serine/threonine protein kinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 335 PF01636: APH" amino acids 43 to 275 (233 residues), 127.7 bits, see alignment E=3.3e-41

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppu:PP_0359)

Predicted SEED Role

"YihE protein, required for LPS synthesis"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88QX5 at UniProt or InterPro

Protein Sequence (335 amino acids)

>PP_0359 serine/threonine protein kinase (Pseudomonas putida KT2440)
MAPRRLPSGATMSHPFDTLTPDLVLDAVESLGFLSDARVLALNSYENRVYQVGIEDAQPL
IAKFYRPGRWSDAAILEEHAFTAELADCEVPVVAPMQHDDRTLFEHKGFRFTLFPRRGGH
APEPGNLDQLYRLGQLLGRLHAVGASKPFKHREALAVDNFGHASLNTLLEGNFVPHELLP
AFESVARDLLKRVEDIYARTPHQLIRLHGDLHPGNLMHRDEVYHVVDLDDCRMGPAVQDL
WMMLAGNREERLGQLAELIDGYNEFHDFDPRELALIEPLRALRQLHYSAWLARRWDDPAF
PPSFPWFGQPRYWGDQILALREQMAALDEAPLKLF