Protein Info for PP_0115 in Pseudomonas putida KT2440

Annotation: hydroperoxidase - self catalytic heme d synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 711 PF00199: Catalase" amino acids 46 to 430 (385 residues), 602.1 bits, see alignment E=9.4e-185 PF06628: Catalase-rel" amino acids 462 to 527 (66 residues), 74.3 bits, see alignment E=1.4e-24 PF18011: Catalase_C" amino acids 562 to 703 (142 residues), 48.2 bits, see alignment E=1.9e-16 PF01965: DJ-1_PfpI" amino acids 564 to 655 (92 residues), 26.9 bits, see alignment E=8.1e-10

Best Hits

Swiss-Prot: 97% identical to CATE_PSEPU: Catalase HPII (katE) from Pseudomonas putida

KEGG orthology group: K03781, catalase [EC: 1.11.1.6] (inferred from 100% identity to ppu:PP_0115)

Predicted SEED Role

"Catalase (EC 1.11.1.6)" in subsystem Oxidative stress or Photorespiration (oxidative C2 cycle) (EC 1.11.1.6)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.11.1.6

Use Curated BLAST to search for 1.11.1.6

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88RL4 at UniProt or InterPro

Protein Sequence (711 amino acids)

>PP_0115 hydroperoxidase - self catalytic heme d synthase (Pseudomonas putida KT2440)
MPSKKTDAPKHSEAAGTQTPDRANTNAKLQSLEADRSDATGQALRTNQGVRIADNQNSLK
AGDRGPSLLEDFIMREKITHFDHERIPERIVHARGTGAHGFFQSYGNHAELTKAGFLQDP
EKITPVFVRFSTVQGPRGSGDTVRDVRGFAVKFYTDEGNFDLVGNNMPVFFIQDAIKFPD
FVHAVKPEPHNEIPTGGSAHDTFWDFVSLVPESAHMVMWAMSDRAIPRSLRMMEGFGVHT
FRLINAEGVASFVKFHWKPRQGVHSLLWDEAQKLAGKDTDFQRRDLWEAIETGDYPEWEL
GVQIVPEADEHKFDFDLLDPTKIIPEELVPVTPLGKMVLNRNPDNFFAEVEQVAFCPGHI
VQGIDFTNDPLLQGRLFSYTDTQISRLGGPNFHQIPINRPVAPNHNNQRDALHQHVVHKG
RASYEPNSIDGGWPKETPPAAQDGGFESYQERIDAHKIRQRSESFGDHFSQARLFFHSMS
PTEQQHIIKAYSFELGKVEREHIRAREVNEILANIDLKLAAAVAANLGLPAPKAGTVKVK
GSQLAQSPALSQMNHPGSVGIKGRKIAVLVADGVDAASVDKLVKALEAHSARPMLLGPTS
APVKAADGKQLPVAASMEGMPSIMFDGIVVPAGKASTDALAASGLAKHFVLEGYKHLKAL
VLTKELAKALGLKEDKGLLLGDEQKAVDAFVKAVEGHRVWEREAAAEAVPA