Protein Info for PP_0057 in Pseudomonas putida KT2440

Annotation: major facilitator family transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 539 transmembrane" amino acids 23 to 48 (26 residues), see Phobius details amino acids 61 to 83 (23 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details amino acids 119 to 139 (21 residues), see Phobius details amino acids 163 to 184 (22 residues), see Phobius details amino acids 196 to 215 (20 residues), see Phobius details amino acids 249 to 273 (25 residues), see Phobius details amino acids 288 to 308 (21 residues), see Phobius details amino acids 317 to 336 (20 residues), see Phobius details amino acids 440 to 465 (26 residues), see Phobius details amino acids 484 to 504 (21 residues), see Phobius details amino acids 510 to 528 (19 residues), see Phobius details PF00083: Sugar_tr" amino acids 25 to 333 (309 residues), 110.8 bits, see alignment E=8e-36 PF07690: MFS_1" amino acids 29 to 333 (305 residues), 89.8 bits, see alignment E=1.7e-29

Best Hits

KEGG orthology group: None (inferred from 100% identity to ppf:Pput_0073)

Predicted SEED Role

"Permeases of the major facilitator superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

See Q88RS2 at UniProt or InterPro

Protein Sequence (539 amino acids)

>PP_0057 major facilitator family transporter (Pseudomonas putida KT2440)
MSDYIQEQGAAASSSSRREERKIIFASSLGTVFEWYDFFLYGALAAVISKQFFAGVNDTT
AFIFALMAFAAGFLVRPFGALVFGRLGDMIGRKYTFLVTIVLMGLSTFAVGLLPTYASIG
IAAPIILVILRMLQGLALGGEYGGAATYVAEHAPPGKRGLHTGFIQSTATLGLLLSLLVV
LGSRYISGDQFETWGWRLPFLLSIVLLAISTWIRMSMHESPAFVKMKAQGKVSKSPIRES
FTSWPNLKVVLTALFSINAGQAVTFYTAQFYVLFFMTQMLKMDSAQANTLLIISVVIGAP
FFVFFGWLSDRIGRKPILMLGLLLATVLYFPLFKALSHYANPQIDAASRQAPIVVTADPQ
GCTFQFDPVGKARFDSPCDKVKTFLVKQGLPYSSVSVAGSEVVVNIGDKTINGFDETAMR
AAIEQAGYPAKADPAQVNQVMVVVLIVAMILIATMTYGPLAAVMVELFPTRIRYTSMSLP
YHIGNGWFGGFLPTVSFALVVYTGDIFYGLWYPVLVTGISLVVGIFCLRETKDVDIDKV