Protein Info for PFR28_04969 in Pseudomonas sp. RS175

Annotation: Glycine betaine transport ATP-binding protein OpuAA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01186: glycine betaine/L-proline transport ATP binding subunit
  • amino acids 41 to 271 (231 residues), 367.6 bits, E=3.6e-114
• PF00005: ABC_tran
  • amino acids 48 to 196 (149 residues), 116.3 bits, E=1.8e-37

Best Hits

KEGG orthology group: K02000, glycine betaine/proline transport system ATP-binding protein [EC: 3.6.3.32] (inferred from 99% identity to pba:PSEBR_a382)

MetaCyc: 34% identical to cystine ABC transporter ATP binding subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"Histidine ABC transporter, ATP-binding protein (TC 3.A.1)"

Isozymes

Compare fitness of predicted isozymes for: 3.6.3.32

Use Curated BLAST to search for 3.6.3.32 or 7.4.2.12

Protein Sequence (276 amino acids)

>PFR28_04969 Glycine betaine transport ATP-binding protein OpuAA (Pseudomonas sp. RS175)
MSNAAVSKIEVKNVFKIFGNRSREALELIRQNKTKDQVLAETGCVVGVNDLSLSIGTGEI
FVIMGLSGSGKSTLVRHFNRLIDPTSGAILVDGEDILQLDMDALREFRRHKISMVFQSFG
LLPHKNVLDNVAYGLKVRGESKQVCAERALHWINTVGLKGYENKYPHQLSGGMRQRVGLA
RALAADTDIILMDEAFSALDPLIRAEMQDQLLELQKTLHKTIVFITHDLDEAVRIGNRIA
ILKDGKLIQVGTPREILHSPADEYVDRFVQRRAAVV