Protein Info for PFR28_04908 in Pseudomonas sp. RS175

Annotation: Soluble epoxide hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 319 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details PF00561: Abhydrolase_1" amino acids 58 to 305 (248 residues), 86 bits, see alignment E=5.2e-28 PF12146: Hydrolase_4" amino acids 59 to 155 (97 residues), 30.3 bits, see alignment E=3.8e-11 PF12697: Abhydrolase_6" amino acids 60 to 307 (248 residues), 63.3 bits, see alignment E=8.3e-21

Best Hits

KEGG orthology group: None (inferred from 73% identity to pba:PSEBR_a437)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (319 amino acids)

>PFR28_04908 Soluble epoxide hydrolase (Pseudomonas sp. RS175)
MKKLISSVLCLFDSMASNQASAALAKRGVVVNGDKFRSEYANVNGIRMHYLVSGNGEKPV
LLVHGFPGSWRNWEALMGRLLRAGYTPIVPDYRGAGETDISASGYDKKNMALDLHELIKT
LGIKQVDIVGHDMGLIIAYAYGALYPEETTHIVLMDGFIPGIPGWEIPYNGNPATGTTSK
WHFRFFGATAIKMIEGKERNYLDMFFDEFVYNDNPRVPDEVRDALVKDYSRPGRMEAAFK
LYSAWVEYDANDNQAFAEHKLNIPVLTIGGDHSRGKTLFTQVQHITSQPQSLILENTGHW
VLEEKMQFTSQAILDFLRN