Protein Info for PFR28_04895 in Pseudomonas sp. RS175
Annotation: Acetylornithine/succinyldiaminopimelate aminotransferase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 89% identity to pba:PSEBR_a308)Predicted SEED Role
"4-aminobutyrate aminotransferase (EC 2.6.1.19)" (EC 2.6.1.19)
MetaCyc Pathways
- 4-aminobutanoate degradation III (2/2 steps found)
- superpathway of L-arginine and L-ornithine degradation (9/13 steps found)
- 4-aminobutanoate degradation I (1/2 steps found)
- 4-aminobutanoate degradation II (1/2 steps found)
- superpathway of L-arginine, putrescine, and 4-aminobutanoate degradation (7/11 steps found)
- superpathway of 4-aminobutanoate degradation (1/3 steps found)
- GABA shunt I (1/4 steps found)
- GABA shunt II (1/4 steps found)
- 4-aminobutanoate degradation V (2/7 steps found)
- nicotine degradation I (pyridine pathway) (4/17 steps found)
KEGG Metabolic Maps
- Alanine and aspartate metabolism
- Butanoate metabolism
- Glutamate metabolism
- Propanoate metabolism
- beta-Alanine metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.19
Use Curated BLAST to search for 2.6.1.19
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (970 amino acids)
>PFR28_04895 Acetylornithine/succinyldiaminopimelate aminotransferase (Pseudomonas sp. RS175) MPLATLVHRASLPSPQLSAAQAVVLLRSNYGLSGDLRPLGSQQDLNLRVDSERGRFVLKI CHGDYAVQELQAQHAALKQLAGNGAVKVPQVIAANNGQDLLTLDVDGQAVHVRLLEYIDG QPLTRLKHMGPELVSGLGRLCAQVDLALASFDHPGLERTLQWDPRHASALIDHLLPVVQD DPRRSLVAEAAQQAERRLHPLKASLPVQAIHMDLTDDNVVWQRDALRQWQVKGVIDFGDL IRTWRITELSVTCAALLHHADGDPFFILPAVQAYHSANPLQREELLALWPLIVTRAAILV LSGEQQASIDPDNAYSRDNLEHEWEIFRVAHSVPFELMEAAILAAVDQSLPPVASEGFAP LLPTLVGREFALIDLGVLSPHFEAGNWEAPGIDRRLLGEAAAVHGLAASRYGQYRLSRTR TDSAEEPDTFPLHVELHVPRGTPLESPFAGVVHKRADGMLQLDGTQLSVRLWGVTSPLHS GAALVKGQVLGEVSEPLLVQLCRGAQLDPPLFCTPSRAAAWQALCPSPSVLLGLACDAEA EVDAKTLLARRDASFARTQKHYYVDPPRIERGWRNHLIDMQGRSYLDMLNNVAVLGHGHP RMAAVAARQWSLLNTNSRFHYASVTEFSERLLALAPPGMDRVFLVNSGTEANDLAIRLAW AYSGGRDMLSVLEAYHGWSVAADAVSTSIADNPQALSSRPDWVHPVTAPNTYRGEFRGPD STPDYLRSVEHSLAKIAERKRQLAGFICEPVYGNAGGIALPPGYLKQVYGLVRERGGVCI ADEVQVGYGRMGEFFWGFEEQGVVPDIITMAKGMGNGQPLGAVITRREIAEALEAEGYFF SSAGGSPVSCQIGIAVLDVMQEERLWENAREVGRYFKARLQALIERHPLVGAVHGSGFYL GLELIRNRDTLEPATEETAALCDRLRELGIFMQPTGDYLNILKIKPPMVTTRQSVDFFVD MLSKVLDEDL