Protein Info for PFR28_04887 in Pseudomonas sp. RS175

Annotation: '3'(2'),5'-bisphosphate nucleotidase CysQ' transl_table=11

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 275 PF00459: Inositol_P" amino acids 8 to 254 (247 residues), 182.7 bits, see alignment E=5.2e-58 TIGR01331: 3'(2'),5'-bisphosphate nucleotidase" amino acids 9 to 258 (250 residues), 284.8 bits, see alignment E=3.3e-89

Best Hits

Swiss-Prot: 52% identical to CYSQ_SHIFL: 3'(2'),5'-bisphosphate nucleotidase CysQ (cysQ) from Shigella flexneri

KEGG orthology group: K03677, CysQ protein (inferred from 91% identity to pba:PSEBR_a300)

MetaCyc: 51% identical to 3'(2'),5'-bisphosphate nucleotidase (Escherichia coli K-12 substr. MG1655)
3'(2'),5'-bisphosphate nucleotidase. [EC: 3.1.3.7]

Predicted SEED Role

"3'(2'),5'-bisphosphate nucleotidase (EC 3.1.3.7)" (EC 3.1.3.7)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (275 amino acids)

>PFR28_04887 '3'(2'),5'-bisphosphate nucleotidase CysQ' transl_table=11 (Pseudomonas sp. RS175)
MNYPHPLMAPVIELALKAGEAILPFWRANVQVDRKADESPVTAADMAAHDVIVAGLTALA
PQIPILSEEDADIAQDLRAGWQRWWLVDPLDGTKEFISGSEEFTVNIALIEQGQVVFGVV
SMPTSGRFYVGGAGLGAWRGDKGGEPSPIEVRHALVPGETFTVVASRRHTSPEQERLLDG
LSQSLGELQLTSIGSSLKFCLVAEGAADCYPRLAPTSQWDTAAAQGVLEGAGGEVLDLSG
EVFCYPPRESLLNASFLALPAKAAWRGKLLELARS