Protein Info for PFR28_04621 in Pseudomonas sp. RS175

Annotation: High-affinity zinc uptake system protein ZnuA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 308 signal peptide" amino acids 1 to 24 (24 residues), see Phobius details PF01297: ZnuA" amino acids 27 to 302 (276 residues), 195.4 bits, see alignment E=6.5e-62

Best Hits

KEGG orthology group: K09815, zinc transport system substrate-binding protein (inferred from 93% identity to pba:PSEBR_a37)

Predicted SEED Role

"Zinc ABC transporter, periplasmic-binding protein ZnuA" in subsystem Transport of Zinc

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (308 amino acids)

>PFR28_04621 High-affinity zinc uptake system protein ZnuA (Pseudomonas sp. RS175)
MSRLFSIFVAFVASFLLIGPAQAEVKVLASIKPLQLIAAAVQDGVAVPEVLLPPGASPHH
YALRPSDVRKVQSVDLLYWIGPDMEGFLPRVLNGRTLPSVAVQELPGLKLRHFGEDSHSH
AEDDHDDEHDHDHRPGTIDAHLWLSPTNARVIAARMAADLSSADPANAARYQSNLKGFNQ
RLDALDARLKSRLAGIADKPYFVFHEAFDYFEDTYGLKHAGVFAVAAEVQPGAQHVAAMR
TRLQAVGKTCVFSEPPLRPRLAETLVAGLPVKLAELDALGGYTPATAQGYEQLLEKLGND
LAGCLESL