Protein Info for PFR28_04597 in Pseudomonas sp. RS175
Annotation: Sensor histidine kinase WalK
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: None (inferred from 83% identity to pba:PSEBR_a8)Predicted SEED Role
"Signal transduction histidine kinase"
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (513 amino acids)
>PFR28_04597 Sensor histidine kinase WalK (Pseudomonas sp. RS175) MSHQRRRESREPTQAQRLFRQLVREWLWISLLLLPLTALLSFSAQPTRNGPAALLSVCLV ACVLGLLLLRPRLALWTTVGGMGLALTLSAVLGAQGWWWSPLASVLGMLFGYLIWNWRRL SVVLAYFGWELARLDAEPKVFPERRRAPYTGSDRLQGQVMALEQAMSRTRDTRRFIADGL EYLPVATMISDPHGKVLLGNRKARELFGRGLAGEDVVEHLAQLGYPGLVPGCPHRLSTLP LLEFRDVQDRSLRLERASLLPADGDVPVGWLLSLTDLSAEREAEEQRNIMLRFLSHDLRA PHSAILALLDVQRNQAGTTDPVFDQIERQVRRALALTDGFVQLARAESEVYQFRPTLFAM LVLDVLDQALPLAQAKHIQIAHDIDDEEAMVSADQALLTRALFNLLENAIKYSPPATRIV VRVRCAEGRLTCDLVDQGKGIEAGELPDLFSQYRRFSSAHGVDGVGLGLSMVKAVVDRHG GQIECRSVVGEGTTFSFGLALLDTEKAQPSVVL