Protein Info for PFR28_04293 in Pseudomonas sp. RS175

Annotation: Spermidine/putrescine import ATP-binding protein PotA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 PF00005: ABC_tran" amino acids 38 to 180 (143 residues), 139.7 bits, see alignment E=1e-44 TIGR01187: polyamine ABC transporter, ATP-binding protein" amino acids 53 to 378 (326 residues), 425.4 bits, see alignment E=6.6e-132 PF08402: TOBE_2" amino acids 300 to 378 (79 residues), 67.9 bits, see alignment E=6.8e-23

Best Hits

KEGG orthology group: K11076, putrescine transport system ATP-binding protein (inferred from 99% identity to pba:PSEBR_a5401)

Predicted SEED Role

"Putrescine transport ATP-binding protein PotG (TC 3.A.1.11.2)" in subsystem Polyamine Metabolism (TC 3.A.1.11.2)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>PFR28_04293 Spermidine/putrescine import ATP-binding protein PotA (Pseudomonas sp. RS175)
MAVASGAYKKALEGDQTPKQVLVKIDRVTKKFDETIAVDDVSLEIKKGEIFALLGGSGSG
KSTLLRMLAGFERPTEGRIFLDGVDITDMPPYERPINMMFQSYALFPHMTVAQNIAFGLQ
QDRIPKAEIEARVAEMLKLVQMSQYAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPM
GALDKKLRSQMQLELVEIIERVGVTCVMVTHDQEEAMTMAERIAIMHLGWIAQIGSPIDI
YETPTSRLVCEFIGNVNIFETEVVDDAEGHAVLTCKDLDRNIYVGHGISTSVQDKSVTYA
IRPEKLLVTAEQPTCEHNWSSGKVHDIAYLGGHSVFYVELPSGKLVQSFVANAERRGQRP
TWGDQVFVWWEDDSGVVLRS