Protein Info for PFR28_04287 in Pseudomonas sp. RS175

Annotation: 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF12146: Hydrolase_4
  • amino acids 67 to 295 (229 residues), 102.6 bits, E=3.3e-33
• PF00561: Abhydrolase_1
  • amino acids 70 to 154 (85 residues), 32.6 bits, E=1e-11
• PF12697: Abhydrolase_6
  • amino acids 72 to 292 (221 residues), 52.8 bits, E=1.4e-17

Best Hits

KEGG orthology group: None (inferred from 92% identity to pba:PSEBR_a5364)

Predicted SEED Role

"Lysophospholipase (EC 3.1.1.5)" in subsystem Triacylglycerol metabolism (EC 3.1.1.5)

MetaCyc Pathways

• phospholipid remodeling (phosphatidylethanolamine, yeast) (2/4 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.5

Use Curated BLAST to search for 3.1.1.5

Protein Sequence (315 amino acids)

>PFR28_04287 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase (Pseudomonas sp. RS175)
MPATFDPDNLRASLQSMAQWQPLSEQARAYQRFYGLDFPQREVRKGLGRFRIDGYELVGQ
VWWPEKAVATLFVFHGYYDHMGLYRHLIEWALAQGFAVIACDLPGHGLSSGERASIGDFA
EYQATLQGLLAEAATLGLPQPWHLCGQSTGGAIVVDHVLNQGADSPAQGQVILLSPLVRP
RAWGWSRLSYYLLKPFVTGIARRFSENSTDPDFLPFLQADPLQPLRLPTAWVGALAQWIK
RIEAAPNSPRRPLIVQGQADMTVDWKHNLQVLCSKFDRPQVMMLPEGRHHLANESLALRQ
EMFGFLNKRMSRNRR