Protein Info for PFR28_04191 in Pseudomonas sp. RS175

Annotation: Homoserine/homoserine lactone efflux protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 206 signal peptide" amino acids 1 to 28 (28 residues), see Phobius details transmembrane" amino acids 43 to 65 (23 residues), see Phobius details amino acids 70 to 91 (22 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 147 to 172 (26 residues), see Phobius details amino acids 184 to 203 (20 residues), see Phobius details PF01810: LysE" amino acids 15 to 202 (188 residues), 75.7 bits, see alignment E=1.8e-25

Best Hits

KEGG orthology group: None (inferred from 93% identity to pba:PSEBR_a5273)

Predicted SEED Role

"Putative threonine efflux protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (206 amino acids)

>PFR28_04191 Homoserine/homoserine lactone efflux protein (Pseudomonas sp. RS175)
MDLTTLAVFIPACFALNMAPGPNNLLSISNASRYGFVRACSGGIGRLVAFAIMIALAAVG
LTAVLHTSEVLFLGIKLVGAGYLFYLAVQLWRAQPEAGSEAAITTISMTSLARQEFLVAI
GNPKAILLFTAFLPQFVDRAGTVTQQFAVLGGLFLALECIAIGLYCYMGIHARRLFAQPS
GKRLFNRMCAGLLAGAASFLLVARRT