Protein Info for PFR28_04031 in Pseudomonas sp. RS175
Annotation: Anhydro-N-acetylmuramic acid kinase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 85% identical to ANMK_PSEPF: Anhydro-N-acetylmuramic acid kinase (anmK) from Pseudomonas fluorescens (strain Pf0-1)
KEGG orthology group: K09001, anhydro-N-acetylmuramic acid kinase [EC: 2.7.1.-] (inferred from 87% identity to pba:PSEBR_a5105)MetaCyc: 67% identical to anhydro-N-acetylmuramic acid kinase monomer (Pseudomonas aeruginosa PAO1)
RXN0-4621 [EC: 2.7.1.170]
Predicted SEED Role
"Anhydro-N-acetylmuramic acid kinase (EC 2.7.1.-)" (EC 2.7.1.-)
MetaCyc Pathways
- peptidoglycan recycling I (11/14 steps found)
- peptidoglycan recycling II (8/10 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 2.7.1.-
Use Curated BLAST to search for 2.7.1.- or 2.7.1.170
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (363 amino acids)
>PFR28_04031 Anhydro-N-acetylmuramic acid kinase (Pseudomonas sp. RS175) MVLYIGVMSGTSLDGLDIALVELTPAIRLIATHYIPMPDSLRSELLGLCTSGPDEIARSA IAQQNWVQLAAHGIHALLESQNLKPEDVRAIGSHGQTIRHEPARGFTVQIGNPALLSELT GITIVSDFRSRDVAAGGQGAPLVPAFHEALFEKRDGNRAVLNVGGFSNLSLIEPGKPVAG FDCGPGNVLLDAWIHQQRNEQFDRDGRWAASGTVEPALLKAMLSDPFFVTKGPKSTGREV FNLPWLTRHLSQLPTLAAENVQATLLELTALTIVESLQNAQADTRELLVCGGGAHNTALM KRLADLMPSTEVSSTAVYGVDPDWVEAMAFAWLAHCCLEYIPANRPSVTGARGLRVLGAI YPA