Protein Info for PFR28_03718 in Pseudomonas sp. RS175

Annotation: Transcriptional regulatory protein ZraR

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 478 PF00072: Response_reg" amino acids 4 to 109 (106 residues), 81.6 bits, see alignment E=1.4e-26 PF00158: Sigma54_activat" amino acids 148 to 314 (167 residues), 246.9 bits, see alignment E=2.6e-77 PF14532: Sigma54_activ_2" amino acids 149 to 319 (171 residues), 86.4 bits, see alignment E=6.5e-28 PF07728: AAA_5" amino acids 171 to 292 (122 residues), 35.9 bits, see alignment E=2.2e-12

Best Hits

KEGG orthology group: None (inferred from 95% identity to pba:PSEBR_a4813)

Predicted SEED Role

"Two-component sensor CbrB: intrcellular carbon:nitrogen balance"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (478 amino acids)

>PFR28_03718 Transcriptional regulatory protein ZraR (Pseudomonas sp. RS175)
MPHILIVEDETIIRSALRRLLERNQYQVSEAGSVQEAQERFSIPTFDLIVSDLRLPGAPG
TELIKLGQGTPVLIMTSYASLRSAVDSMKMGAVDYIAKPFDHDEMLQAVARILRDRQTAA
NNPAEPTNGKAATSAKTVAGNANGEIGIIGSCPPMQDLYVKIRKVAPTDSNVLIQGESGT
GKELVARALHNLSRRAKAPMISVNCAAIPESLIESELFGHEKGAFTGASAGRAGLVEAAD
GGTLFLDEIGELPLEAQARLLRVLQEGEIRRVGSVQSQKVDVRLIAATHRDLKSLAKIGQ
FREDLYYRLHVIALKLPALRERGADVNEIANAFLARQSARVNRTDLKFAPDAEQAIRHYA
WPGNVRELENAVERAVILCESPEISADLLGIDIELSDMDDEEFIGLAPQQGNAANNTSHE
PTEDLSLEDYFQHFVLEHQDHMTETELARKLGVSRKCLWERRQRLGIPRRKTGVASES