Protein Info for PFR28_03667 in Pseudomonas sp. RS175

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 48 to 71 (24 residues), see Phobius details amino acids 83 to 102 (20 residues), see Phobius details amino acids 122 to 147 (26 residues), see Phobius details amino acids 153 to 172 (20 residues), see Phobius details amino acids 183 to 201 (19 residues), see Phobius details amino acids 213 to 231 (19 residues), see Phobius details PF03741: TerC" amino acids 14 to 203 (190 residues), 150.3 bits, see alignment E=7.8e-48 PF00571: CBS" amino acids 372 to 423 (52 residues), 30.4 bits, see alignment 6e-11 PF03471: CorC_HlyC" amino acids 440 to 515 (76 residues), 66.1 bits, see alignment E=3.3e-22

Best Hits

Swiss-Prot: 57% identical to YEGH_ECOLI: UPF0053 protein YegH (yegH) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 89% identity to pba:PSEBR_a2916)

Predicted SEED Role

"Membrane protein, TerC family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>PFR28_03667 hypothetical protein (Pseudomonas sp. RS175)
MEWIVDPTAWLGLLTLIVLELVLGIDNLVFIAILADKLPPAQRDRARIIGLSLALLMRLG
LLASISWMVTLTAPLFEVYGKTFSGRDLIMLFGGVFLLFKATMELHERLEGHVVQRSGQG
AYAMFWPIVAQIVVLDAVFSLDAVITAVGMVEHLSVMMIAVIFSIGLMIIASKPLTRFVN
GHPTVIMLCLGFLMMIGFSLTAEGLGFHIPKGYLYAAIGFSILIELFNQVARLRRRKSLH
GQRPMRERTAHAVLRLLGGRKPDADEVGEEIADMLAGNDTDQVFDRRERVMISGVLQLAE
RPIRTVMTPRAEVDHIDVADSPENIRTRLMHSSYSRLPLIREGRVDEPLGFVHKKELFKE
LLAGNQPNLQTMARKAINLLDTFTILNALEQMRKESTHIAFVVNEFGDFVGLLTMTDILE
SIAGELPDASEIEGPNIVAREDGFLVSGALNLSQVGEHTGLQAKATDDYQTLAGMVMSLL
DRLPVIGDRLNWQEWSMTVVEVQERRVTRVLLRKEEA