Protein Info for PFR28_03598 in Pseudomonas sp. RS175

Annotation: Penicillin-binding protein activator LpoA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 603 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF04348: LppC" amino acids 33 to 593 (561 residues), 602.6 bits, see alignment E=7.9e-185 PF13458: Peripla_BP_6" amino acids 251 to 530 (280 residues), 36.8 bits, see alignment E=3.9e-13

Best Hits

KEGG orthology group: K07121, (no description) (inferred from 95% identity to pba:PSEBR_a4632)

Predicted SEED Role

"LppC putative lipoprotein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (603 amino acids)

>PFR28_03598 Penicillin-binding protein activator LpoA (Pseudomonas sp. RS175)
MIACLRLFSALCLAALLAACASSPSSSLGELPRTPDASIEQLLEQAAQSKTPEKAALLRL
SAADLAYRQGNAGQSAQILQQVPLEQLKPGQQIFASTLSAELAMTRNQPKAALAALSHPS
QQHLGEMPVEQQIRTGTVHARALEADGQTLAAARERIFIAPLLENEAAAKNHEAIWSLIA
SLPTDQLQPSTTDDLGGWLSLARAVKTAGTLEQQQAAIDSWREQNPKHPAAIQLPTPLVK
LKELASQPLSKIALLLPQNGQLATVAKALREGFMAAHYQAQQAGQNPPSIQFYDSTNLTS
MDEFYRKAQADGVQLVVGPLEKPLVKQISTRPQLPITTLALNYSEGEQGPPQLFQFGLAP
EDEAREVARRARADGLHRAAAMVPKGEWGDRVLKAFSQDWQANGGTIVAIERVDQPVQLA
QQIADMFQLRQSEARAKSLQSTVGTTVAAQPSRRQDIEFIFLASTPQQAQQIKPTLNFQY
AGDVPVYATSQVFSASGDQNQYNDMNGIRFCETPWLLDANDPLRKQVTAQWPQAGGSLGR
LYAMGADAYRLAPRLGQLKTLPDSRIEGLSGSLAVSQSQRIQRQLPWAEFVNGQVQRLPD
TQR