Protein Info for PFR28_03486 in Pseudomonas sp. RS175

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 signal peptide" amino acids 1 to 33 (33 residues), see Phobius details transmembrane" amino acids 263 to 284 (22 residues), see Phobius details amino acids 488 to 506 (19 residues), see Phobius details PF19443: DAHL" amino acids 33 to 255 (223 residues), 185.8 bits, see alignment E=9.7e-59 PF02518: HATPase_c" amino acids 483 to 594 (112 residues), 64.6 bits, see alignment E=1.1e-21

Best Hits

KEGG orthology group: None (inferred from 89% identity to pba:PSEBR_a4515)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (600 amino acids)

>PFR28_03486 Adaptive-response sensory-kinase SasA (Pseudomonas sp. RS175)
MSPLRRISLLLVGLLLASILLFMYVNSSAQQAASYIESRDLIRLLKQQDAIWDNEVLKSR
IALSHNYDPLVSPLHEMTRLWQRLDAIESEPGRHTPSRWEGLRDEYLKAVKEKTRLVEQF
KSHNAVLRNSLAFLPTAEDDIQAQFAQLPDTEKLQLQSVTIDTYDLLLSSMEFSHLTTPE
VAAEVLLGLNRLDINKERLPAGLGGSVDILSRHIALILREQPRVNELLQGIEAVPVSDHL
DAITHLLEKDQETAAGKHQRNHVYLLVFATFLVLILIWLAIRLVRSFAEIKRVNSALQSA
NDELEQRVEERTRQLKDTQSELMDTARQAGMAEIATNVLHNVGNVLNSVNISADLVSRKL
RGSKAQGLGKAMQLINEHPHDLGHFLTEDEKGKLLPGYLNQLVEAMAVEQQGLLDELAQL
SKSVDHIKDIVSTQQSYAGANSLMEPLVVSELLEDALRMNSGALTRHHVTVIKEYGDVPR
IMGDKHRLLLILINLISNAKYAMAGVSNHARNMTLSAQVVDGETLQISVKDEGEGIPAQN
MTRIFAHGFTTRKEGHGFGLHSCALAAIEMNGHLTAHSDGPGTGATFVLQVPLKLAEGEP