Protein Info for PFR28_03482 in Pseudomonas sp. RS175

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 454 PF00072: Response_reg" amino acids 15 to 126 (112 residues), 93.7 bits, see alignment E=8.4e-31 PF13487: HD_5" amino acids 194 to 359 (166 residues), 140.7 bits, see alignment E=4.2e-45

Best Hits

KEGG orthology group: None (inferred from 94% identity to pba:PSEBR_a4511)

Predicted SEED Role

"Response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (454 amino acids)

>PFR28_03482 Sensor histidine kinase RcsC (Pseudomonas sp. RS175)
MEDQSPDVPVTKPTVLLVDDEESILNSLRRLLRSQPYEILLADSGAKALEILKERPVDLV
MTDARMPNMDGATLLAHIRKLYPSTLRILLTGYADVDMMTKAINEGQLYRYLSKPWNDEE
LVQALRQALAHQHSENERQRLEALNREQNQQLKTLNATLEKRVASRTAELQQTADMLDLA
YEELKRSYVTGTEVFSLIANLRLPKAKQTNRQIIELIRVYSRLHFLDESTDRDLTMAAAL
YNIGKLSWTDNMMTTPADLLHHNELELYRAYPKQSESLLMTLDPMKDAARIILHHQERWD
GSGFPDHLKGEAIPFGSRLLKLAVDFIELQRGLILERQMNSDEALVYIRKYAGKLYDPDM
VEDFIKACGEYLEDVTLSDPTVKVMNTRELTAGMVLARNLNADNGMLLLNAGKVLSAPLV
DKLIAFEAMEGARYSVFVKIPEEADPAAPKPMLG