Protein Info for PFR28_03427 in Pseudomonas sp. RS175

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 678 transmembrane" amino acids 16 to 42 (27 residues), see Phobius details amino acids 156 to 179 (24 residues), see Phobius details PF00672: HAMP" amino acids 185 to 234 (50 residues), 35.6 bits, see alignment 2.3e-12 TIGR00229: PAS domain S-box protein" amino acids 288 to 403 (116 residues), 31.1 bits, see alignment E=1.1e-11 PF00989: PAS" amino acids 289 to 394 (106 residues), 40.3 bits, see alignment E=7.4e-14 PF08448: PAS_4" amino acids 294 to 397 (104 residues), 34.8 bits, see alignment E=4.3e-12 PF00512: HisKA" amino acids 415 to 498 (84 residues), 27.1 bits, see alignment E=8.6e-10 PF02518: HATPase_c" amino acids 552 to 664 (113 residues), 85.4 bits, see alignment E=9.2e-28

Best Hits

KEGG orthology group: None (inferred from 96% identity to pba:PSEBR_a4454)

Predicted SEED Role

"Sensory box histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (678 amino acids)

>PFR28_03427 Sensor histidine kinase RcsC (Pseudomonas sp. RS175)
MPLRQRLENLPVGQKLLAALLVLLTTVLLVANLTFISAAYYISQESMAPQALQTIGRLIA
NPSLISDALKSPQNARRLLDELNNYAPLRAAALYDGDGERLAQLQQGEKLKLPDHFRTMQ
AWQAGEFRSNQVITLPRPGQSPGHLLLVASSELPTAFYTGTLTASLGILIFSVLLWLVIA
QQIKRLITQPIHQLEELSRQVTREENYSLRAARGNHDEIGSLAEAFNTMLSRIEAREQQL
KRARDDSQAAYDQAQGLAEETRHTNRKLELEVQVRSKIEKKLTGFQNYLNSIIDSMPSAL
IALDEQLYVTQWNQEASALSGTRLDEALNQPIFLAFEPLKPYLPQLKQTVEQHTVAKIER
VTWTKDDEARHYALTFYPLMGGAGRGVVIRIDDITQRLSLEEMMVQSEKMLSVGGLAAGM
AHEINNPLGAILHNVQNIRRRLSPELPKNLEQAEQLGIELQVVNRYLEGRDIPQLLDGIQ
QAGARAAKIVTHMLSFSRRSTRQMAPCDLPALIDQAVEIAGNDFDLAIGFDFKGQAIIRQ
FDPNLGPVPGTANELEQVLLNLLKNAAQAIHQRQDNSEPGRIILRTRLNPPWAEIQVEDN
GIGMSENVRKRTFEPFFTTKEVGQGTGLGLSVSYFIITNNHKGQMEVQSAPGQGTCFTLR
LPLAGASMAPQENKQLER