Protein Info for PFR28_03189 in Pseudomonas sp. RS175

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1156 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 39 to 60 (22 residues), see Phobius details amino acids 66 to 87 (22 residues), see Phobius details amino acids 116 to 135 (20 residues), see Phobius details amino acids 161 to 178 (18 residues), see Phobius details amino acids 191 to 217 (27 residues), see Phobius details amino acids 241 to 261 (21 residues), see Phobius details amino acids 282 to 305 (24 residues), see Phobius details amino acids 328 to 355 (28 residues), see Phobius details amino acids 382 to 402 (21 residues), see Phobius details amino acids 411 to 433 (23 residues), see Phobius details amino acids 441 to 465 (25 residues), see Phobius details amino acids 489 to 511 (23 residues), see Phobius details PF00474: SSF" amino acids 39 to 448 (410 residues), 26 bits, see alignment E=1.1e-09 PF12860: PAS_7" amino acids 642 to 756 (115 residues), 151.2 bits, see alignment E=3.2e-48 PF00512: HisKA" amino acids 797 to 863 (67 residues), 49.1 bits, see alignment 1.2e-16 PF02518: HATPase_c" amino acids 908 to 1016 (109 residues), 78.8 bits, see alignment E=1.1e-25 PF00072: Response_reg" amino acids 1039 to 1149 (111 residues), 49.1 bits, see alignment E=1.5e-16

Best Hits

KEGG orthology group: None (inferred from 96% identity to pba:PSEBR_a4228)

Predicted SEED Role

"Sensory box histidine kinase/response regulator"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1156 amino acids)

>PFR28_03189 Sensor histidine kinase RcsC (Pseudomonas sp. RS175)
MSLSSGLIAVVALAYMAIMFAIAFYGDRRSTPLPPRVRAWVYSLSLAVYCTSWTFFGAVG
QAAEQLWSFLPIYLGPILLLVLAPWVLQKMVLISKQENITSIADFIAARYGKSQSLAIVI
ALICLVGVLPYIALQLKGIVLGVNLLIGAGADAMGTRAQDTALIVSLILALFTIVFGTRN
LDATEHHRGMVLAIAFESLVKLFAFLAVGAFVTFGLYDGFDDLFNQAMLAPRLEQYWKET
INWPSMVVQTGVAMMAIICLPRQFHVTVVENIDPQDLRLAKWVFPAYLALAALFVVPIAL
AGQMMLPSSVLPDSFVISLPLAQAHPSLAVLAFIGGASAATGMVIVASVALSTMVSNDML
LPWLLRRNNAERPFEVFRQWMLSVRRVSIVVILLLAYVSYRLLGSTASLATIGQIAFAAV
TQLAPAMLGALYWKQANRRGVFAGLAAGIFLWFYTLVLPIAAHSLGWSLDSFPGLAWLHG
NPLDLPITPLTQGVVLSLAGNFSLFAWVSLLSRTRVSEHWQAGRFIGQEISPRPNARSML
AVHIEDLLQLAARFVGEERARQSFIRFAYRQGKGFNPNQNADSEWIAHTERLLAGVLGAS
STRAVVKAAIEGREMQLEDVVRIADEASEVLQFNRALLQGAIENITQGISVVDQSLRLVA
WNRRYLELFNYPDGLISVGRPIADIIRYNAERGLCGPGEAEVHVARRLHWMRQGRAHTSE
RLFPNGRVIELIGNPMPGGGFVMSFTDITAFREAEQALTEANEGLEQRVAERTRELSQLN
QALTEAKSTAEAAYQSKTRFLAAVSHDLMQPLNAARLFSAALSHQHDSLPSEARQLVQHL
DSSLRSAEDLITDLLDISRLENGKINPDRKPFALNELFDILGAEFTALAQEQGLKFRVRG
SRLRVDSDIKLLRRILQNFLTNAFRYAKGPVLLGVRRRNGELCLEVWDRGPGIAEDKQQV
IFEEFKRLDSHQTRAEKGLGLGLAIADGLCRVLGHTLRVRSWPGRGSVFSVSVPLARTQN
AVPSAVVEPNGVLPSGAQVLCVDNEDSILIGMNSLLTRWGCQVRTARNREECESWLAQGG
RPQLALVDFHLDGGETGTELMAWLRKRMGEPVPGVVISADGRPETVAQVHAAGLDFLAKP
VKPAALRALLSRHLPL