Protein Info for PFR28_03156 in Pseudomonas sp. RS175

Annotation: putative M18 family aminopeptidase 2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 429 PF02127: Peptidase_M18" amino acids 12 to 423 (412 residues), 472.2 bits, see alignment E=1.6e-145 PF05343: Peptidase_M42" amino acids 316 to 417 (102 residues), 23.2 bits, see alignment E=3.3e-09

Best Hits

Swiss-Prot: 96% identical to APEB_PSEPF: Probable M18 family aminopeptidase 2 (apeB) from Pseudomonas fluorescens (strain Pf0-1)

KEGG orthology group: None (inferred from 99% identity to pba:PSEBR_a4195)

Predicted SEED Role

"Aspartyl aminopeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (429 amino acids)

>PFR28_03156 putative M18 family aminopeptidase 2 (Pseudomonas sp. RS175)
MRAELNQGLIDFLKASPTPFHATASLAKRLEAAGYQRLDERETWATEANGRYYVTRNDSS
IIAFKLGRNAPLHDGIRLVGAHTDSPCLRVKPQPELQRHGFWQLGVEVYGGALLAPWFDR
DLSLAGRVTFRRDGKVESQLIDFKAPIATIPNLAIHLNREANQGWAINPQNELPPILAQF
AGDERVDFRAVLTDQLAREHGLNADVVLDYELSFYDTQSAAIVGLHGDFIAGARLDNLLS
CYAGLQALLNADTEETCVLVCNDHEEVGSCSACGADGPMLEQTLRRLLPEGEEFVRTIQK
SLLVSADNAHGVHPNYADKHDANHGPKLNAGPVIKVNSNQRYATNSETAGFFRHLCMAEE
VPVQSFVVRSDMGCGSTIGPITASQLGVRTVDIGLPTFAMHSIRELCGSHDLAHLVKVLS
AFYASRELP