Protein Info for PFR28_02984 in Pseudomonas sp. RS175

Annotation: D-galactonate transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 436 transmembrane" amino acids 20 to 35 (16 residues), see Phobius details amino acids 56 to 75 (20 residues), see Phobius details amino acids 87 to 115 (29 residues), see Phobius details amino acids 147 to 168 (22 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 248 to 269 (22 residues), see Phobius details amino acids 286 to 309 (24 residues), see Phobius details amino acids 321 to 339 (19 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 377 to 400 (24 residues), see Phobius details amino acids 407 to 428 (22 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 394 (369 residues), 198.4 bits, see alignment E=8.2e-63 TIGR00893: D-galactonate transporter" amino acids 28 to 428 (401 residues), 418.9 bits, see alignment E=1e-129

Best Hits

Swiss-Prot: 42% identical to GUDP_ECOLI: Probable glucarate transporter (gudP) from Escherichia coli (strain K12)

KEGG orthology group: K08194, MFS transporter, ACS family, D-galactonate transporter (inferred from 98% identity to pba:PSEBR_a4024)

MetaCyc: 42% identical to galactarate/D-glucarate transporter GudP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-203; TRANS-RXN0-204; TRANS-RXN0-523

Predicted SEED Role

"Hexuronate transporter" in subsystem Alginate metabolism or D-Galacturonate and D-Glucuronate Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (436 amino acids)

>PFR28_02984 D-galactonate transporter (Pseudomonas sp. RS175)
MQAHTLSAQASLVTPSRKRFFIMVLLFITVVINYLDRSNLSIAAPALTSDLGIDPIHVGL
IFSAFGWTYAAMQIPGGWLVDRVPPRILYSVALLLWSVATVMLGFAASFIALFVLRMAVG
ALEAPAYPINSRVVTTWFPERERATAIGFYTSGQFVGLAFLTPVLAWLQHTFGWHMVFVV
TGAVGVLWAVIWYAVYREPRDFKGANAAEIELIREGGGLVDIQAETARVKAKFSWADLGI
VLTQRKLWGIYLGQFCLNSTLWFFLTWFPTYLVKYRGMDFIKSGLLASLPFLAAFVGVLC
SGFFSDWLIRRGATVGFARKLPIIGGLLISTSIIGANFVESTPLVIAFLALAFFGNGLAS
ITWSLVSTLAPARLLGLTGGVFNFIGNLAAIATPIVIGFLASGDSFAPAITYISVLALAG
ALSYILLVGKVERIEL