Protein Info for PFR28_02958 in Pseudomonas sp. RS175

Annotation: 1-acyl-sn-glycerol-3-phosphate acyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00530: 1-acylglycerol-3-phosphate O-acyltransferases
  • amino acids 62 to 181 (120 residues), 144.4 bits, E=8.1e-47
• PF01553: Acyltransferase
  • amino acids 65 to 181 (117 residues), 121.9 bits, E=8.2e-40

Best Hits

KEGG orthology group: K00655, 1-acyl-sn-glycerol-3-phosphate acyltransferase [EC: 2.3.1.51] (inferred from 86% identity to pba:PSEBR_a4002)

Predicted SEED Role

"1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)" in subsystem Glycerolipid and Glycerophospholipid Metabolism in Bacteria or Phosphate metabolism (EC 2.3.1.51)

MetaCyc Pathways

• superpathway of phospholipid biosynthesis III (E. coli) (11/12 steps found)
• phosphatidylglycerol biosynthesis I (6/6 steps found)
• phosphatidylglycerol biosynthesis II (6/6 steps found)
• CDP-diacylglycerol biosynthesis I (4/4 steps found)
• CDP-diacylglycerol biosynthesis II (4/4 steps found)
• superpathway of cardiolipin biosynthesis (bacteria) (10/13 steps found)
• oleate biosynthesis III (cyanobacteria) (2/3 steps found)
• palmitoleate biosynthesis III (cyanobacteria) (1/2 steps found)
• phospholipid remodeling (phosphatidate, yeast) (1/2 steps found)
• CDP-diacylglycerol biosynthesis III (3/5 steps found)
• phosphatidate biosynthesis (yeast) (3/5 steps found)
• diacylglycerol and triacylglycerol biosynthesis (3/7 steps found)
• palmitoyl ethanolamide biosynthesis (2/6 steps found)
• superpathway of stearidonate biosynthesis (cyanobacteria) (2/6 steps found)
• stigma estolide biosynthesis (2/7 steps found)
• anandamide biosynthesis II (2/8 steps found)
• anandamide biosynthesis I (3/12 steps found)
• superpathway of phospholipid biosynthesis II (plants) (10/28 steps found)
• plasmalogen biosynthesis I (aerobic) (1/16 steps found)

KEGG Metabolic Maps

• Glycerolipid metabolism
• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.3.1.51

Use Curated BLAST to search for 2.3.1.51

Protein Sequence (240 amino acids)

>PFR28_02958 1-acyl-sn-glycerol-3-phosphate acyltransferase (Pseudomonas sp. RS175)
MLFVLRMLLLGLHFILAGVLGLILGVCRPFNPDNSRLCARLYAWPAMWILGLRLKAGVDT
LANKPRSCVIIANHQSNYDLFVFGSVVPRRTVCIGKKSLKWVPLFGQLFWLAGNVLIDRG
NAIKARRAMLTTTHTLQHEDTSIWVFPEGTRNLGHELLPFKKGAFQMAIAAGVPIVPVCV
SNYVNHMRLNRWRSGDILIRSLPAIPTAGLSMEDMPRLMNQCREQMHECIESMDRQIRKS