Protein Info for PFR28_02844 in Pseudomonas sp. RS175

Annotation: Methyl-accepting chemotaxis protein McpP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 559 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details transmembrane" amino acids 204 to 228 (25 residues), see Phobius details PF08269: dCache_2" amino acids 36 to 191 (156 residues), 74.6 bits, see alignment E=1.6e-24 PF17200: sCache_2" amino acids 50 to 190 (141 residues), 73.7 bits, see alignment E=3.2e-24 PF00672: HAMP" amino acids 225 to 278 (54 residues), 54.7 bits, see alignment 2e-18 PF00015: MCPsignal" amino acids 343 to 523 (181 residues), 134.8 bits, see alignment E=6e-43

Best Hits

Swiss-Prot: 72% identical to MALCR_PSEAE: Methyl-accepting chemotaxis protein PA2652 (PA2652) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K03406, methyl-accepting chemotaxis protein (inferred from 96% identity to pba:PSEBR_a3887)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (559 amino acids)

>PFR28_02844 Methyl-accepting chemotaxis protein McpP (Pseudomonas sp. RS175)
MRLSLKAKVLSLAILPVLLSAVIISLTTAFILKEQAANEVRQTRERLLAEAKATLQNYVA
VGLTAIKPLYDAAAPGDNAARAQAIKLLSNVSYGKDGYFFGYDSETVRLFKANSPDGVGK
SFKDNRDPNGVYVNRDLVKVAKDGTHYLEYSSPLPNSNELVPKLGYTEYLPKWDMAVGSS
VNLDGIEGQVALVEAKVHDRVQGVILSIVGIAAVVLLVIAVVGLLLANTILRPLHLMKDN
LDDIAAGEGDLTRRLPITSQDELGQLAGSFNRFVDKIHGLVRQITDMTSQLTGLVTQVSE
QAQRSEQAMERQRHETDQVATAINQMSSAAQEVARSAQGAAVAAQQTDEEGQSAKRVVAG
SIQQIHALVNDIRSSGLSLDSLQQDVASIVSVLGVIRSIAEQTNLLALNAAIEAARAGEA
GRGFAVVADEVRALASRTQQSTQEIQGMIDRLQSGTHAAVEAMRRSSEAGDGTSVQANEA
GASLDAMAQLIGTINSMNAQIASAAEEQTAVAEEINRSVHQIAVAVDSVADETQRGAQTS
RSLNDLGQRLGKLVGQFRI