Protein Info for PFR28_02733 in Pseudomonas sp. RS175

Annotation: Ribokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00294: PfkB
  • amino acids 3 to 295 (293 residues), 245.8 bits, E=6.8e-77
• TIGR02152: ribokinase
  • amino acids 5 to 300 (296 residues), 367.1 bits, E=3.6e-114
• PF08543: Phos_pyr_kin
  • amino acids 179 to 277 (99 residues), 40 bits, E=3.2e-14

Best Hits

Swiss-Prot: 45% identical to RBSK_ECO57: Ribokinase (rbsK) from Escherichia coli O157:H7

KEGG orthology group: K00852, ribokinase [EC: 2.7.1.15] (inferred from 89% identity to pba:PSEBR_a3707)

MetaCyc: 45% identical to ribokinase (Escherichia coli K-12 substr. MG1655)
Ribokinase. [EC: 2.7.1.15]

Predicted SEED Role

"Ribokinase (EC 2.7.1.15)" in subsystem D-ribose utilization or Deoxyribose and Deoxynucleoside Catabolism (EC 2.7.1.15)

MetaCyc Pathways

• ribose phosphorylation (2/2 steps found)
• 2-deoxy-D-ribose degradation I (2/3 steps found)

KEGG Metabolic Maps

• Pentose phosphate pathway

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.15

Protein Sequence (304 amino acids)

>PFR28_02733 Ribokinase (Pseudomonas sp. RS175)
MPAKVVVIGSLNMDLVTRAPRLPRGGETLIGESFSTIAGGKGANQAVAAARLGAQVAMVG
CVGSDAYGQQLRGALVNEGIDCQAVSVVEGSSGVALIVVDGNSQNAIVIVAGANGALTPA
VLDGFDEVLQSADVIVCQLEVPDATVAHALKRGRELGKIVILNPAPASHALPADWYACVD
YLIPNESEAAMLSGLAVDSLETAEAAAAQLIGAGAGKVIVTLGGQGLMFANGSSFEHFPA
PRVKAVDTTAAGDTFVGGFAAALANGKSEVEAIRLGQVAAALSVTRIGAQPSIPTLQEVQ
AFES