Protein Info for PFR28_02558 in Pseudomonas sp. RS175

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 729 PF13185: GAF_2" amino acids 28 to 168 (141 residues), 32.4 bits, see alignment E=4.1e-11 PF01590: GAF" amino acids 29 to 168 (140 residues), 37.6 bits, see alignment E=1.2e-12 TIGR00229: PAS domain S-box protein" amino acids 186 to 311 (126 residues), 43.5 bits, see alignment E=1.6e-15 PF00989: PAS" amino acids 206 to 301 (96 residues), 22.9 bits, see alignment E=2.9e-08 PF08447: PAS_3" amino acids 213 to 298 (86 residues), 52 bits, see alignment E=2.8e-17 PF08448: PAS_4" amino acids 215 to 305 (91 residues), 26.8 bits, see alignment E=2.1e-09 PF00512: HisKA" amino acids 353 to 418 (66 residues), 32.6 bits, see alignment E=2.6e-11 PF02518: HATPase_c" amino acids 460 to 579 (120 residues), 67.2 bits, see alignment E=6.6e-22 PF00072: Response_reg" amino acids 606 to 715 (110 residues), 68.3 bits, see alignment E=2.6e-22

Best Hits

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (729 amino acids)

>PFR28_02558 Sensor histidine kinase RcsC (Pseudomonas sp. RS175)
MIPMAIEDTLLRQRKVLAEFGELALASDDLEHILDQACRLVSEALDTHLAKFMWLEEDGV
TFLVRNGVGWTPDVVGQVRVQALPGTPERYSLQTSSPVISTDIATETRFRYHDFQIRNGV
RAFVNVLVYDAGQKHPFGIFEVDSRSPRLFSESDIDFLRGYGNLLGAAQRRVNALQAMRR
SEEKLRESERHYRIAAELNPLWPWTADSLGAVLTLDQRWYEYTGRSPTQTLGRQWLNAAH
PDDRIAFARLWTLSLTTLQPFDTQLRLRKSNGEYRWFRIRALCSLGPAGECEQWYGTVED
IHERVQLENALRDWNDRLEERIAKRTEQLEREQRERTLAESKLRQSQKMEAVGQLTGGIA
HDFNNLLAGITSSLELMQRHIDQGRYDELSRYNSVALTSATRAAALTQRLLTFSRQQSLQ
PEVFEPRIVVAGLEEMIRRSVGPSIQVECSFSGNDPIRCDPNGLENALLNLAINARDAMP
GGGALKLNVHSCLIDEQSADEKMLPSGPYVDISVVDTGTGISADILSRVFDPFFTTKPIG
EGSGLGLSMIYGFVQQSGGQVRIRSSVGVGTTVTMYFPVVSQPSATTPQPGSEETTSLQP
GNNETILLVDDEAAIRQMVAEFLAETGYRVIESLDSVSALKQAEKTGPVDLLLTDIGLPG
AMNGIALAREMRARHPRLKVLFITGFAEGERLVTADAHTRILTKPFSLNELGQRVSSLIQ
TGNDGAGPA