Protein Info for PFR28_02451 in Pseudomonas sp. RS175

Annotation: Biotin biosynthesis cytochrome P450

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 375 PF00067: p450" amino acids 207 to 349 (143 residues), 42.8 bits, see alignment E=1.6e-15

Best Hits

KEGG orthology group: None (inferred from 71% identity to pba:PSEBR_a3386)

Predicted SEED Role

"putative cytochrome p450 oxidoreductase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (375 amino acids)

>PFR28_02451 Biotin biosynthesis cytochrome P450 (Pseudomonas sp. RS175)
MDPITAATHPDPYPYYASLRAKGGLTFDQQVQSWIASSAEAVCAVLRHADCHVRPPQEPV
PKAIAGRPAGQVFGHLMRMNEGERQRCPRSAIAPGLQDIDRQQVRAWVRAGFFEDGAAGL
HHAQFIGPVAVVAALLGFSPADSRLLSALTRDFVACLSPLSDAAQLHAAHRATGQLQVLF
RKRIEANDSASAWLTGICQGFAGVAPNDLVANLIGLLAQTHEATAGLIGNALLALIRDPA
LLHRIREEPTLIGPLQAEVQRFDPPVQNTRRFVVARCDILGVSLEPGEAIVVLLASANRD
PALNPQPDLLLTDRLNRRSFSFGAGRHECPGQTLAMDIAAASLATILERAPQPDRLDWRY
RPSVNGRIPVFSDRP