Protein Info for PFR28_02432 in Pseudomonas sp. RS175

Annotation: Adaptive-response sensory-kinase SasA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 transmembrane" amino acids 18 to 38 (21 residues), see Phobius details amino acids 159 to 182 (24 residues), see Phobius details amino acids 421 to 438 (18 residues), see Phobius details PF00672: HAMP" amino acids 182 to 233 (52 residues), 47.4 bits, see alignment 1.9e-16 PF02518: HATPase_c" amino acids 350 to 453 (104 residues), 83.9 bits, see alignment E=1.1e-27

Best Hits

KEGG orthology group: None (inferred from 94% identity to pba:PSEBR_a3363)

Predicted SEED Role

"sensor histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (461 amino acids)

>PFR28_02432 Adaptive-response sensory-kinase SasA (Pseudomonas sp. RS175)
MSLLNPAKGWRSSSSRLLALYSALFVIWSALLMGVMYYEVFGYLDSLAKHSLMQRQHLFA
RIHADQLEDALMASLTLDERGVDAYGLFDPQLRHLSGPIQRIPADLPLDGKIHMLGGCVD
SDAPGVPSDSCDAVATRTQDGRWLVLARDNGSLFAVTHIILRALFWGVSLTILPGLAGWH
LLRRRPLQRIRKLQASAEAIVAGDLTHRLPLSSRRDELDMLAAIVNAMLDRIERLMNEVK
GVCDNIAHDLRTPLTRLRAQLYRIQQEAAEGSPEALQMDQVIAETDTLMARFRGLLRISE
LEDQQRRSGFVRLDPLQLLQELHDFYLPLAEERELTFRLDVPETLPLLNGDRALLFEAVS
NLLSNSIKFTPPGGEVVLRGVDQGDSTRIEVLDSGPGIPEAERKAVFRRFYRAEGSSQHG
GFGLGLSIVAAIVNLHGFTLEVDSSEQGGARLALDCRATLL