Protein Info for PFR28_02425 in Pseudomonas sp. RS175

Annotation: 5-dehydro-2-deoxygluconokinase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 645 TIGR04382: 5-dehydro-2-deoxygluconokinase" amino acids 11 to 335 (325 residues), 404.5 bits, see alignment E=1.5e-125 PF00294: PfkB" amino acids 13 to 328 (316 residues), 158.2 bits, see alignment E=3.1e-50 PF09863: DUF2090" amino acids 331 to 643 (313 residues), 436.2 bits, see alignment E=6.3e-135

Best Hits

KEGG orthology group: K03338, 5-dehydro-2-deoxygluconokinase [EC: 2.7.1.92] (inferred from 94% identity to pba:PSEBR_a3356)

Predicted SEED Role

"5-keto-2-deoxygluconokinase (EC 2.7.1.92) / uncharacterized domain" in subsystem Inositol catabolism (EC 2.7.1.92)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.7.1.92

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (645 amino acids)

>PFR28_02425 5-dehydro-2-deoxygluconokinase (Pseudomonas sp. RS175)
MGQTRFASGRQLDVICLGRLGVDLYAQQVGARLEDVTSFAKYLGGSSANIAFGTARLGLR
SAMLSRVGDDHMGRFLVESLAREGCDVSGIKVDPQRLTALVLLGIKDRETFPLVFYRENC
ADMALRAEDIDEAFIASSKALLITGTHFSTDSVYKASIQALDHAQKHNVRRILDIDYRPV
LWGLAGKADGETRFVADQTVSRHVQGILPRFDLIVGTEEEFLIAGGSTDLLAALRTVRSL
TAATLVVKLGPQGCTVIHGAIPDRLEDGAIYPGVKVEVLNVLGAGDAFMSGFLAGWLEEA
DDARCCQLANACGGLVVSRHACAPAMPTRAELDYLFDSPVPITRPDQDVALQRLHQVSVP
RRAWKQLFIFAFDHRWQLVELAQKGDRDLSSIGALKQLFIQAVERVEVDLRRQGIEADVG
LLADQRFGQDSLNAATGRGWWVARPVEVQGSRPLAFEHGRSIGSNLIAWPGEQIIKCLVQ
FHPDDEPLLRLEQEAQLMGLYKASQVSGHELLLEVIPPKDHPSPHPDVLYRALKRLYNLG
IFPAWWKIEAQTAEQWKQLDELIQQRDPYCRGVVLLGLNAPASALAEGFRQASQSATCRG
FAVGRTIFQEPSRAWLAGEIDDETLIRQVQGTFVELIDAWRAARA