Protein Info for PFR28_02347 in Pseudomonas sp. RS175

Annotation: Xylose operon regulatory protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 391 PF00532: Peripla_BP_1" amino acids 51 to 270 (220 residues), 22.6 bits, see alignment E=1.4e-08 PF13377: Peripla_BP_3" amino acids 115 to 275 (161 residues), 122.4 bits, see alignment E=4.2e-39 PF12833: HTH_18" amino acids 310 to 388 (79 residues), 70 bits, see alignment E=3.6e-23 PF00165: HTH_AraC" amino acids 350 to 388 (39 residues), 47.8 bits, see alignment 2.2e-16

Best Hits

Swiss-Prot: 46% identical to XYLR_ECO57: Xylose operon regulatory protein (xylR) from Escherichia coli O157:H7

KEGG orthology group: K02529, LacI family transcriptional regulator (inferred from 95% identity to pba:PSEBR_a2598)

Predicted SEED Role

"Xylose activator XylR (AraC family)" in subsystem Xylose utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (391 amino acids)

>PFR28_02347 Xylose operon regulatory protein (Pseudomonas sp. RS175)
MKTVPPVHRIALLFNGSKIYDRGIISGIGNYLSSTRASWDLFLEEDFLCRLKGIERWQGD
GIIADFDDPLIGEALAGIRLPVVAVGGSYEDERAYPKGIPYVATDNFALMKLAYEHLIEA
GLTRFACFSLPVAQANRWAQERERAFRSLLQRDGLHVEVYRGMGTSAPLWDSAVEQQIAW
LQSLPKPIGIIAVSDARARQLLQACLTAGIAVPEQVALIGIDNDPLTRSLTRVPLSSVIQ
GTETMGRTAARLLHQMLHGMPSTGTQVLIPPDAINVQASSLHQPLGNPYVMQALLFIRQY
ACQGIKTAQVAAYVGVSRSSLEAHFRKVRGCSVHDEILRFKLAAAASGLEKTDSPIADIA
RQCGFKSAQYLHTVFRREFGCTPREYQQGAT