Protein Info for PFR28_02344 in Pseudomonas sp. RS175

Annotation: Chaperone protein HscC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 568 PF00012: HSP70" amino acids 2 to 73 (72 residues), 47.9 bits, see alignment E=9.8e-17 amino acids 79 to 543 (465 residues), 407.3 bits, see alignment E=1.5e-125 PF06723: MreB_Mbl" amino acids 93 to 190 (98 residues), 30.5 bits, see alignment E=2.7e-11

Best Hits

KEGG orthology group: K04045, molecular chaperone HscC (inferred from 64% identity to ctu:CTU_25580)

Predicted SEED Role

"Chaperone protein DnaK" in subsystem Heat shock dnaK gene cluster extended or Protein chaperones

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (568 amino acids)

>PFR28_02344 Chaperone protein HscC (Pseudomonas sp. RS175)
MIVGIDLGTTHSLIAAWRDGAAQLVPNALGEWLTPSVVGLDDEGRMMVGRAALERLQTHP
QVTTALFKRYMGSARLTALGNRQFRAEELSAMVLRSLREDAERHFGEPVEEAVISVPAYF
NDAQRKATRIAGELAGFKVERLVNEPTAAALAYGLHQRDNASTFLVFDLGGGTFDVSILE
LFEGVMEVRASAGDNYLGGEDFDTLLLQAFVSAQGKSAAGPVPLGDAQLFSRLHREAERV
RRALGHEPSATFSVRQGDREWHQPYTQAEMAGLYAPLFARLRAPIETALRDARIRASELD
EVLLVGGTTRMPLVRKLVASLFGRFPSIQLNPDEAVALGAAVQAGLKSRDAALEEVVLTD
VCPYSMGIEISVDYGGKLESGHYLPIIERNCVVPVSRVKRVVTLRDQQKMVLLKVYQGES
RQVSENILLGELEIPVPPMPAGEVSIDVRFTYDTNGLLEADAQTVQTGERHKLVITNNTG
LLDEADIARRLEALAALKVHPRDEQPNTVLIARLERLYQESRGDLRQRVDDLATRFAQVL
ETQELHDIRALRMQISEQLDTLERDVWR