Protein Info for PFR28_01993 in Pseudomonas sp. RS175

Annotation: Type I secretion system membrane fusion protein PrsE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 441 transmembrane" amino acids 26 to 45 (20 residues), see Phobius details TIGR01843: type I secretion membrane fusion protein, HlyD family" amino acids 23 to 440 (418 residues), 347.4 bits, see alignment E=6.2e-108 PF00529: CusB_dom_1" amino acids 62 to 395 (334 residues), 38.8 bits, see alignment E=7.2e-14 PF13437: HlyD_3" amino acids 292 to 394 (103 residues), 47.8 bits, see alignment E=2.1e-16

Best Hits

KEGG orthology group: K02022, (no description) (inferred from 65% identity to avn:Avin_16250)

Predicted SEED Role

"HlyD family secretion protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (441 amino acids)

>PFR28_01993 Type I secretion system membrane fusion protein PrsE (Pseudomonas sp. RS175)
MNPATPDRRIESPTELPTSDRKIRRLGIAIVGVTFGLFGTWAAVAPIDGAAYAPGVVTVQ
SYRKTVQHLEGGIVKTLLAHDGDIVQRDDPLIILDDAQLRFEYEISRNQLVATKAMEARL
RAERDELATIDFGGASGPASLRAEEARQGETQVFNARRGARAGQVAVLRERIGQLQQQVK
GLESMIAAKAHLERSYGGEITELGDLLKQGFVDKQRLVEQERKLGLLRSELADHRSSINR
TRLQINETQLQILQIDKDFNADVVKQLAEVQGRMYDLQEKTSALEDRLSRIVIRAPDAGM
VIGMTVHTIGGVVSPATPLLDIVPSVSELVIEAQVAPVDIDRIAIGKRADIRFGAFDSAT
TPVIEGEVSSVSADRLTQEKTGTAYYLARVRVTANGARTLGERKLLPGMPADVLIITGER
TLLQYLMQPARAALSQSMIEE