Protein Info for PFR28_01943 in Pseudomonas sp. RS175

Annotation: Putative isomerase YbhH

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 360 PF04303: PrpF" amino acids 1 to 352 (352 residues), 405.6 bits, see alignment E=2e-125

Best Hits

Swiss-Prot: 63% identical to YBHH_ECOLI: Putative isomerase YbhH (ybhH) from Escherichia coli (strain K12)

KEGG orthology group: K09788, hypothetical protein (inferred from 91% identity to pba:PSEBR_a2303)

MetaCyc: 51% identical to 4-oxalomesaconate tautomerase (Pseudomonas putida KT2440)
RXN-9983 [EC: 5.3.2.8]

Predicted SEED Role

"FIG00958979: hypothetical protein"

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.2.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (360 amino acids)

>PFR28_01943 Putative isomerase YbhH (Pseudomonas sp. RS175)
MQRIPCVLMRGGTSKGPVFLAWDLPASVTERDELLLDLMGSGHELEIDGIGGGSPQTSKV
AIVSPSLHPEADVDYLFVQVMVSQRRVDTAPNCGNMLCAVGPFAIEQGLVKAGGDLTRVR
IRNLNTGTFVVSEVQTPGGKVSYEGDTAIDGVPGTAAPVQLTFLDAAGSKTGKLFPTGQV
LDLIDGILVTCIDMAMPMVIVEASQLGKRGDESPAELDADHDFLQRLESLRLKAGLAMGL
GDVSDKVIPKPVLVSPASSGGTLQVRYFMPHNCHRALAITGSIGLATACVTEGSVAARLT
GGPGEPRLQRVRIEHPSGAIDVVLSYVGEHGETIRASVVRTARRLFSGFVYAKASHRLAG