Protein Info for PFR28_01724 in Pseudomonas sp. RS175

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 556 PF00512: HisKA" amino acids 187 to 252 (66 residues), 38.2 bits, see alignment E=1.8e-13 PF02518: HATPase_c" amino acids 295 to 415 (121 residues), 72.3 bits, see alignment E=6.7e-24 PF00072: Response_reg" amino acids 440 to 551 (112 residues), 63.1 bits, see alignment E=4e-21

Best Hits

KEGG orthology group: None (inferred from 93% identity to pba:PSEBR_a3077)

Predicted SEED Role

"Sensory box sensor histidine kinase/response regulator (EC 2.7.3.-)" (EC 2.7.3.-)

Isozymes

Compare fitness of predicted isozymes for: 2.7.3.-

Use Curated BLAST to search for 2.7.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (556 amino acids)

>PFR28_01724 Sensor histidine kinase RcsC (Pseudomonas sp. RS175)
MTLAEPLSERALILAPLGRDSQIALMILNEAGFAGLICRHLGQLCEELEKGAGLLVISSE
ALVGPDLETLFLEIEQQPAWSDLPIVLLTHHGGPEQNPAARIGMQLGNVTFLERPFHPVT
LVSLVTTALRGRRRQYEARDRLIDLSNSELRLQNTLETLEQQVEERTAQLRHNEEALRQS
QKMEAVGQLTGGIAHDFNNMLTGIIGSLELLRRRLARGRTEDLDSLIDLGVTSANRAAGL
THRLLAFSRRQSLDPKAVQMNTLVLSMGELLQRSLNESIRLDMHLDNQLWIAEADPNQLE
SALLNLVLNARDAMPDGGKLVVQTYNQYLDTGFTDAYTNLEPGDYVVLSVQDTGCGMPEA
VVSRAFDPFFTTKPIGQGTGLGLSMIYGFSKQSHGHVTIDSVVGQGTTVNLYLPRFKGEE
VQEPKVDAQHTPHAQDGETVLIVEDDPAVRVLVSAVLSELGYTFLEAADANGAIPILQSD
QRIDLLVSDVGLPGMNGRQLAEIGRQIRPDLRVLFITGYAEHAAVRGGFLDPGMQMITKP
FTFDLLTAKVREMIRA