Protein Info for PFR28_01620 in Pseudomonas sp. RS175

Annotation: Pyruvate/proton symporter BtsT

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 686 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 35 to 53 (19 residues), see Phobius details amino acids 93 to 113 (21 residues), see Phobius details amino acids 119 to 140 (22 residues), see Phobius details amino acids 161 to 184 (24 residues), see Phobius details amino acids 191 to 210 (20 residues), see Phobius details amino acids 222 to 241 (20 residues), see Phobius details amino acids 257 to 277 (21 residues), see Phobius details amino acids 285 to 304 (20 residues), see Phobius details amino acids 326 to 346 (21 residues), see Phobius details amino acids 366 to 386 (21 residues), see Phobius details amino acids 466 to 485 (20 residues), see Phobius details amino acids 511 to 530 (20 residues), see Phobius details amino acids 543 to 567 (25 residues), see Phobius details amino acids 574 to 596 (23 residues), see Phobius details amino acids 642 to 663 (22 residues), see Phobius details PF02554: CstA" amino acids 33 to 409 (377 residues), 581.8 bits, see alignment E=5.9e-179 PF13722: CstA_5TM" amino acids 464 to 592 (129 residues), 144.7 bits, see alignment E=1.7e-46

Best Hits

Swiss-Prot: 71% identical to CSTA_ECOLI: Peptide transporter CstA (cstA) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 98% identity to pba:PSEBR_a2762)

MetaCyc: 71% identical to pyruvate transporter CstA (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-335

Predicted SEED Role

"Carbon starvation protein A"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (686 amino acids)

>PFR28_01620 Pyruvate/proton symporter BtsT (Pseudomonas sp. RS175)
MTTRLVKHLAWFAVAVLGACALSVVALRRGEPINALWIVVAAVAIYLVAYRYYSLFIANN
VMQLDARRATPAVLNNDGLDYVPTNKHILFGHHFAAIAGAGPLVGPVLAAQMGYLPGTLW
LIAGVVLAGAVQDFMVLFLSTRRNGRSLGDMVREEMGRIPGTIALFGCFLIMIIILAVLA
LIVVKALAESPWGIFTVMATIPIAMFMGIYMRYIRPGRIGEISLIGVLLLLGSIWLGGQV
AADPVWAKAFTFTGVQITWMLIGYGFVAAVLPVWLILAPRDYLSTFLKIGTIVALAIGIL
ITMPELKMPALTQFTDGTGPVWKGGLFPFLFITIACGAVSGFHALISSGTTPKLLDNEVN
ARYIGYGGMLMESFVAIMAMVAASVIEPGVYFAMNSPAAIVGTDVVAVAQTVSNWGFAIT
PDALQAVAKDIGETTILARAGGAPTLAVGIAQILHSVLPGENTMAFWYHFAILFEALFIL
TAVDAGTRAGRFMLQDLLGSFVPALKRTESWPANLIATAGCVALWGYLLYQGVIDPLGGI
NTLWPLFGISNQMLAGIALMLGTVVLIKMKRQRYVWVTLLPATWLLICTTTAGLIKLFDA
NPAIGFLALARKYNDALAAGQVLAPAKSVEQMQHVVFNAYTNATLTVLFLFVVFSILFYA
LKVGIAAWGTKERTDKEAPFQALPDA