Protein Info for PFR28_01496 in Pseudomonas sp. RS175

Annotation: Sensor histidine kinase RcsC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1071 transmembrane" amino acids 21 to 40 (20 residues), see Phobius details amino acids 331 to 353 (23 residues), see Phobius details PF00512: HisKA" amino acids 486 to 551 (66 residues), 72.3 bits, see alignment 5.6e-24 PF02518: HATPase_c" amino acids 598 to 710 (113 residues), 89.2 bits, see alignment E=4.9e-29 PF00072: Response_reg" amino acids 843 to 951 (109 residues), 89.3 bits, see alignment E=3.8e-29 PF01627: Hpt" amino acids 986 to 1065 (80 residues), 47.3 bits, see alignment 4e-16

Best Hits

KEGG orthology group: None (inferred from 62% identity to pfl:PFL_3921)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1071 amino acids)

>PFR28_01496 Sensor histidine kinase RcsC (Pseudomonas sp. RS175)
MTHSDDLLQKLTSSSLKMNKGLIVLGGLASLLIGLSAWGLNRMIEEQRDTVRFHFARLME
NIGEQDAFLDAIARQSAKGLPLDTGQFRMFVEEPLPDEGDGIYKGQELSFSLPFSVKINP
ATIEPGERHRVFGLGAHLASYYSAFWSASYYQSPQVFLFNMPDNFDIAVPAAGRLRGVGQ
IQGGTYQQVMNQILQRLHEDNPRPADSRVHWVRYSAETDNSAPPTVLAYINIDMPATQLG
IRGASPWVVVASLLNLNQLNEIERIMEWSIYDRFSLVAPNGALLVGAEKPGQDLKDGLNF
RLDGLVFKISSDGQQPWTAVYVVGFKSFIDYAWWPLLGMLTLMLASIGGGWAFNRWYKTR
VVLPAHEAHQSIAESEAFSRAIIDSAPTGLCVIRRSDHKILLQNQRLQQWQPSDKLIAAL
EQRQLLTRAGQTELQIDGRHLQVGFVGARYHGQEVWICAFNDVTRHIEDAAALEQALHAA
DSANAAKTRFLATMSHEIRTPLYGVLGTLELLGLTDLAPRQQEYLRTIQRSSATLFQLIS
DVLDVSKIEAGQMTIEAQDFCPLELTEETLRAYSAFAQAKGLQLYACIDPAVPDQVRGDP
LRIRQILNNLVSNAIKFTDNGRVVLRLRVLDKNADVASLLWQVSDSGIGISQAQQAQLFD
PFYQVRDASSEAGAGLGLAICRWLCELMAGELKVVSEPGLGSSFSLQLKLACGQGHLGDC
PQFDPHTPPVYVQAPTPELAQHVCNWLERLGQETRIVNPEQPPCASSLLLDVLPSSQESS
WTGPRIIARAAGPNPPEYTRAGWTVDAYDIRAMAWAIRFAQQGTDSRTFPSTMEPPRHLD
LNILVAEDNPINRAIIKEQLQALGCSVVATANGEQALHQWLPGSFDLVLTDVNMPVMNGY
ELAQALRRNEPDLPIIGVTANALRDEGERCAAVGMNAWLVKPLNLHMLRTQLLKHCKLAE
PLPFSPAPPAADTVHNADRPQLSPKMRDLFLSTMQQDIDTLNATLQGNDTAAVARQLHSM
AGALGAVQAADLAQTCIDLENRLEGRHMTPDLAGDIEAMLGRLRAMLDALA