Protein Info for PFR28_01466 in Pseudomonas sp. RS175

Annotation: L-cystine transport system permease protein YecS

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 218 transmembrane" amino acids 16 to 41 (26 residues), see Phobius details amino acids 49 to 73 (25 residues), see Phobius details amino acids 79 to 100 (22 residues), see Phobius details amino acids 135 to 155 (21 residues), see Phobius details amino acids 185 to 205 (21 residues), see Phobius details TIGR01726: amino ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine family" amino acids 10 to 107 (98 residues), 98.6 bits, see alignment E=1.2e-32 PF00528: BPD_transp_1" amino acids 32 to 213 (182 residues), 70.2 bits, see alignment E=9.9e-24

Best Hits

Swiss-Prot: 44% identical to YECS_SHIFL: L-cystine transport system permease protein YecS (yecS) from Shigella flexneri

KEGG orthology group: K02029, polar amino acid transport system permease protein (inferred from 93% identity to pfl:PFL_2283)

MetaCyc: 44% identical to cystine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-290 [EC: 7.4.2.12]; 7.4.2.12 [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]; 7.4.2.- [EC: 7.4.2.12]

Predicted SEED Role

"ABC-type amino acid transport system, permease component"

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.12

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (218 amino acids)

>PFR28_01466 L-cystine transport system permease protein YecS (Pseudomonas sp. RS175)
MFLQNALDFLPILLKGAVVTLQVTAGSFVLSSLIGLVLALMMVSRIRAIALFAISVVNVI
RGLPIIVQLFYIYFVLPEFGIQLTAMQAGIIGLGIAYSAYQAENFRAGIQAIQQGQIEAA
ESLGMRGAMVMRRVVLPQALRIALPPYGNTLVMMLKDSSLVSTITVAEMTRAGQLIASST
FENMTVYTLVALLYLAMSLPLSFALRRLEARLSTRRTS