Protein Info for PFR28_01438 in Pseudomonas sp. RS175

Annotation: Cyclic di-GMP phosphodiesterase response regulator RpfG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 PF00072: Response_reg" amino acids 11 to 122 (112 residues), 89.1 bits, see alignment E=3.4e-29 PF13487: HD_5" amino acids 164 to 331 (168 residues), 116.5 bits, see alignment E=1.7e-37 PF01966: HD" amino acids 176 to 299 (124 residues), 71.2 bits, see alignment E=1.4e-23

Best Hits

KEGG orthology group: K07814, putative two-component system response regulator (inferred from 91% identity to pba:PSEBR_a2255)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (350 amino acids)

>PFR28_01438 Cyclic di-GMP phosphodiesterase response regulator RpfG (Pseudomonas sp. RS175)
MFTKVNAESRIVIIDDVPTNLRLLDSCLRAVGLRNITTFNDSAQGLDWLLSNAWDLVLLD
LDMPAPDGFEILDRLNKRDRTESPVIIVTALNDQQNRRKGLEKGANDFISKPIDLPEVLL
RVRNCLELAQAAKLLRDVNAELERKVELRTVQLASSYKAISSSLSRAASYRDDDTGQHIV
RIGESSALLAKAIGMPSQWCELLKMAAPMHDIGKIGIADAILQKPGALTPQEREVMQEHA
RIGYEILHDPDGSPLTDLAAEIALAHHERWDGTGYPKGLRGKEIPLSARIVSICDVYDAI
RMPRAYKQAWDVERSRRFITDQAGTQFDPSLVDVFCNLFDEVDRLRLPDV