Protein Info for PFR28_01305 in Pseudomonas sp. RS175

Annotation: Aldose 1-epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01263: Aldose_epim
  • amino acids 45 to 378 (334 residues), 313 bits, E=1.2e-97

Best Hits

Swiss-Prot: 46% identical to GALM_ACICA: Aldose 1-epimerase (mro) from Acinetobacter calcoaceticus

KEGG orthology group: K01785, aldose 1-epimerase [EC: 5.1.3.3] (inferred from 92% identity to pba:PSEBR_a1887)

MetaCyc: 46% identical to mutarotase (Acinetobacter calcoaceticus)
Aldose 1-epimerase. [EC: 5.1.3.3]

Predicted SEED Role

"Aldose 1-epimerase (EC 5.1.3.3)" in subsystem Lactose and Galactose Uptake and Utilization or Maltose and Maltodextrin Utilization (EC 5.1.3.3)

MetaCyc Pathways

• trehalose degradation VI (periplasmic) (2/2 steps found)
• D-galactose degradation I (Leloir pathway) (3/5 steps found)

KEGG Metabolic Maps

• Glycolysis / Gluconeogenesis

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.3

Protein Sequence (383 amino acids)

>PFR28_01305 Aldose 1-epimerase (Pseudomonas sp. RS175)
MLESRHLLTALGVALMIATPASQAAGLTNEHGPFGKTDDGSPVEKYVLRNSHGMQATVIT
YGAILQSLVVPDKNGKAADVVLGFDDVQGYQKNGSVYFGATIGRFGNRLADGAFELDGKR
YQVPQNDHGNSLHGGPQGFDKRVWKAVPHDGKDSVGVTLTYLSADGEMGFPGALKTDVTY
SLNEQNELRIDYQATTDKPTVLNLTNHSYFNLAGAGNGDILKQVATLHASHYTPVTGKLI
PTGELAPVAGTPMDFTKPIAIGTHIKADHPQLKFAEPKQGGFDFNWVLDAKGDVSKPAAD
VYDPQSGRRLQLYTTEPGVQFYTSNFLDGTVKGKQGKTYPHWGAFTLETQHFPDSPNQPN
FPSTRLDPGQTYTQTMVLKFSAK