Protein Info for PFR28_01072 in Pseudomonas sp. RS175

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 580 TIGR00229: PAS domain S-box protein" amino acids 3 to 119 (117 residues), 55.1 bits, see alignment E=8.1e-19 PF08448: PAS_4" amino acids 13 to 119 (107 residues), 38 bits, see alignment E=6e-13 PF13426: PAS_9" amino acids 13 to 116 (104 residues), 62.8 bits, see alignment E=1.1e-20 PF00989: PAS" amino acids 14 to 99 (86 residues), 41 bits, see alignment E=6.2e-14 PF08447: PAS_3" amino acids 25 to 110 (86 residues), 49.7 bits, see alignment E=1.3e-16 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 124 to 288 (165 residues), 141.2 bits, see alignment E=2.7e-45 PF00990: GGDEF" amino acids 130 to 285 (156 residues), 152.5 bits, see alignment E=3.1e-48 PF00563: EAL" amino acids 305 to 540 (236 residues), 230 bits, see alignment E=9.7e-72

Best Hits

KEGG orthology group: None (inferred from 89% identity to pba:PSEBR_a1711)

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (580 amino acids)

>PFR28_01072 hypothetical protein (Pseudomonas sp. RS175)
MDKKYRRAVDAAAIFSETDLNGRITYVNDQFCLLFGYRRDELLGENHRLLNSGQHPGEFF
SAMWRTIALGQIWKGEICNRAKDGTLHWVDTTLVPVADDTTGRIERYLAIRFDVSEKRRQ
LHSLQWRVGHDVLTGLPNRTYLSDLLNQSLAFSRAENLPLAICMLDLDGFKAVNDGHGHA
SGDRLLVEVARRLRSIVRGEDVVARLAGDEFVLVLRHVRGMDELHGALNRVLIAVSAPYV
IDGKSIKVFASIGVTLYPCDDEDAETLLRHADQAMYVAKQSGRNRFHLFDVSRDREVQAT
YQSVERVRQALVDDELRLHFQPKVNMRDGCVVGLEALLRWKHPQRGLVPPREFLPLVEET
DLIVDIGEWVMEQVMTQLQQWQQAGQCWPVSINISARHFQRADFVARLRQVLERHPTVSP
RMLDLQIVESVAVENLAHVSDCLQACQALGVVFSLGGFGTGHCSLNDLKHLRTQTIKIDK
TFVRDILEDRDDLALTRAVIGLAQAFGRQVVAEGLDSLEHGQLLLRLGCEVAQGYFIARP
MPPEQIPGWVRGFVPPPQWKQRPGIQGDSVSACDAALRPV