Protein Info for PFR28_00873 in Pseudomonas sp. RS175

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 402 transmembrane" amino acids 6 to 24 (19 residues), see Phobius details amino acids 94 to 113 (20 residues), see Phobius details signal peptide" amino acids 25 to 25 (1 residues), see Phobius details TIGR03142: cytochrome c-type biogenesis protein CcmI" amino acids 4 to 116 (113 residues), 106.7 bits, see alignment E=4.4e-35 PF14559: TPR_19" amino acids 137 to 185 (49 residues), 26.5 bits, see alignment 1.3e-09 PF13432: TPR_16" amino acids 138 to 178 (41 residues), 23.5 bits, see alignment 1.4e-08 amino acids 207 to 253 (47 residues), 20.1 bits, see alignment 1.5e-07

Best Hits

Swiss-Prot: 67% identical to CYCH_PSEAE: Cytochrome c-type biogenesis protein CycH (cycH) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02200, cytochrome c-type biogenesis protein CcmH (inferred from 94% identity to pba:PSEBR_a1518)

Predicted SEED Role

"Cytochrome c heme lyase subunit CcmH" in subsystem Biogenesis of c-type cytochromes or Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (402 amino acids)

>PFR28_00873 hypothetical protein (Pseudomonas sp. RS175)
MIDFWLAAGLLLLVALSFLLIPVLRGRRAQREEDRTALNVALYQERVAELQAEQAEGVLN
AAQLDTGRAEAARELLADTEGVDAPRESRLGKPLPLLAAVLVPVLGLGLYLHFGASDKVE
LTREFAQAPQSMQDMTQRLERAVAAQPDNAEGLYFLGRTYMAQDRPADAAKIFERTVAVA
GRQPELLGQWAQAQYFADGKKWSDKVQALTDEALKLDPKEVTSLGLLGIAAFEGERYQDA
IDYWGRLLEQLPQGDKSREALQGGIARATEKLQASGGKVAQAPAVAAKAAALLKVRVDLA
PALKAKVQPGDSVFIFARAVSGPPAPLAAKRLTVADLPASVELGDADAMMPQLKLSNFPE
VQLVARISRAGQPTAGEWIGRSQPLASSTTTPQQLTIDSPDQ